Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells

Reem Aboushousha, Evan Elko, Shi B. Chia, Allison M. Manuel, Cheryl van de Wetering, Jos van der Velden, Maximilian MacPherson, Cuixia Erickson, Julie A. Reisz, Angelo D'Alessandro, Emiel F. M. Wouters, Niki L. Reynaert, Ying-Wai Lam, Vikas Anathy, Albert van der Vliet, David J. Seward, Yvonne M. W. Janssen-Heininger

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number21525
Number of pages16
JournalFaseb Journal
Volume35
Issue number5
DOIs
Publication statusPublished - May 2021

Keywords

  • asthma
  • glutathionylation
  • glycolysis
  • inflammation
  • PYRUVATE-KINASE M2
  • GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
  • DENDRITIC CELL
  • METABOLOMICS
  • HIF-1-ALPHA
  • INHIBITION
  • METABOLISM
  • EXPRESSION

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