Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers: A randomized double-blind 7-Tesla pharmacological MRS study

Claudia Vingerhoets*, Desmond H.Y. Tse, Mathilde van Oudenaren, Dennis Hernaus, Esther van Duin, Janneke Zinkstok, Johannes G. Ramaekers, Jacobus Fa Jansen, Grainne McAlonan, Therese van Amelsvoort

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number0269881120922977
Pages (from-to)856-863
Number of pages8
JournalJournal of Psychopharmacology
Volume34
Issue number8
Early online date25 May 2020
DOIs
Publication statusPublished - Aug 2020

Keywords

  • Glutmate
  • GABA
  • 22q11
  • 2DS
  • riluzole
  • cognition
  • H-1-MRS
  • voltage-gated sodium channel blocker
  • MAGNETIC-RESONANCE
  • PROTON SPECTROSCOPY
  • HUMAN BRAIN
  • RILUZOLE
  • SCHIZOPHRENIA
  • QUANTITATION
  • PSYCHOSIS
  • DYSFUNCTION
  • MECHANISMS

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