Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling

Jordi Requena, Ana Belen Alvarez-Palomo, Montserrat Codina-Pascual, Raul Delgado-Morales, Sebastian Moran, Manel Esteller, Marti Sal, Manel Juan, Anna Boronat Barado, Antonella Consiglio, Orleigh Addeleccia Bogle, Ernst Wolvetang, Dmitry Ovchinnikov, Inaki Alvarez, Dolores Jaraquemada, Jovita Mezquita-Pla, Rafael Oliva, Michael J. Edel*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)476-488
Number of pages13
JournalStem Cells
Volume37
Issue number4
DOIs
Publication statusPublished - Apr 2019

Keywords

  • Cytokine
  • Human leukocyte antigen
  • Immune response
  • Induced pluripotent stem cells
  • Inflammation
  • MHC-I
  • Neural stem cells
  • Toll like receptor
  • IMMUNOGENICITY
  • BIOINFORMATICS
  • EXPRESSION
  • ACTIVATION
  • NEURONS
  • ROLES

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