Global Deletion of 11β-HSD1 Prevents Muscle Wasting Associated with Glucocorticoid Therapy in Polyarthritis

J.M. Webster*, M.S. Sagmeister, C.G. Fenton, A.P. Seabright, Y.C. Lai, S.W. Jones, A. Filer, M.S. Cooper, G.G. Lavery, K. Raza, R. Langen, R.S. Hardy

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number7828
Number of pages14
JournalInternational Journal of Molecular Sciences
Volume22
Issue number15
DOIs
Publication statusPublished - 1 Aug 2021

Keywords

  • sarcopenia
  • myopathy
  • steroids
  • adverse effects
  • 11beta hydroxysteroid dehydrogenase type 1
  • rheumatoid arthritis
  • inflammation
  • TUMOR-NECROSIS-FACTOR
  • DEHYDROGENASE TYPE-1
  • EXPRESSION
  • INHIBITION
  • METABOLISM
  • PROFILES

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