Glaucoma management : economic evaluations based on a patient level simulation model

Intensive intraocular pressure reduction can prevent blindness from glaucoma. While effective in some patients, it may be unnecessarily intensive in other patients, leading to a burden on quality of life and general health care consumption. It is hard to tell in advance which scenario will apply to a particular patient. This dissertation describes how a simulation model for disease progression was used to evaluate intensive glaucoma treatment in terms of long term health and economic consequences. It also describes the evaluation of a method to assess the potential value of implementing more personalized care in glaucoma.