Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice

Klytaimnistra Kiouptsi, Giulia Pontarollo, Hristo Todorov, Johannes Braun, Sven Jaeckel, Thomas Koeck, Franziska Bayer, Cornelia Karwot, Angelica Karpi, Susanne Gerber, Yvonne Jansen, Philipp Wild, Wolfram Ruf, Andreas Daiber, Emiel van der Vorst, Christian Weber, Yvonne Doering, Christoph Reinhardt*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1809-1823
Number of pages15
JournalGut Microbes
Volume11
Issue number6
DOIs
Publication statusPublished - 1 Nov 2020

Keywords

  • Microbiota
  • germ-free
  • low-density lipoprotein receptor-deficient mouse
  • atherosclerosis
  • aortic root
  • aortic arch
  • macrophages
  • smooth muscle cells
  • inflammatory markers
  • age
  • lesion size
  • GUT MICROBIOTA
  • BILE-ACIDS
  • CHOLESTEROL
  • METABOLISM
  • HYPERCHOLESTEROLEMIA
  • TRIMETHYLAMINE
  • INFLAMMATION
  • SEX

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