Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer

Manjie Xing, Wen Fong Ooi, Jing Tan, Aditi Qamra, Po-Hsien Lee, Zhimei Li, Chang Xu, Nisha Padmanabhan, Jing Quan Lim, Yu Amanda Guo, Xiaosai Yao, Mandoli Amit, Ley Moy Ng, Taotao Sheng, Jing Wang, Kie Kyon Huang, Chukwuemeka George Anene-Nzelu, Shamaine Wei Ting Ho, Mohana Ray, Lijia MaGregorio Fazzi, Kevin Junliang Lim, Giovani Claresta Wijaya, Shenli Zhang, Tannistha Nandi, Tingdong Yan, Mei Mei Chang, Kakoli Das, Zul Fazreen Adam Isa, Jeanie Wu, Polly Suk Yean Poon, Yue Ning Lam, Joyce Suling Lin, Su Ting Tay, Ming Hui Lee, Angie Lay Keng Tan, Xuewen Ong, Kevin White, Steven George Rozen, Michael Beer, Roger Sik Yin Foo, Heike Irmgard Grabsch, Anders Jacobsen Skanderup, Shang Li, Bin Tean Teh, Patrick Tan*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)3005-3020
Number of pages16
JournalJournal of Clinical Investigation
Volume130
Issue number6
DOIs
Publication statusPublished - 1 Jun 2020

Keywords

  • B-CELL FACTOR-1
  • GROUP PROTEIN EZH2
  • PROMOTER MUTATIONS
  • TRANSCRIPTION FACTORS
  • TELOMERASE ACTIVITY
  • DIFFERENTIATION
  • CAPECITABINE
  • CHEMOTHERAPY
  • PROGRESSION
  • RECOGNITION

Cite this

Xing, M., Ooi, W. F., Tan, J., Qamra, A., Lee, P-H., Li, Z., Xu, C., Padmanabhan, N., Lim, J. Q., Guo, Y. A., Yao, X., Amit, M., Ng, L. M., Sheng, T., Wang, J., Huang, K. K., Anene-Nzelu, C. G., Ho, S. W. T., Ray, M., ... Tan, P. (2020). Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer. Journal of Clinical Investigation, 130(6), 3005-3020. https://doi.org/10.1172/JCI126726