Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro

Senthilkumar A. Natesan, Alex J. Bladon, Serdar Coskun, Wafa Qubbaj, Renata Prates, Santiago Munne, Edith Coonen, Joseph C. F. M. Dreesen, Servi J. C. Stevens, Aimee D. C. Paulussen, Sharyn E. Stock-Myer, Leeanda J. Wilton, Souraya Jaroudi, Dagan Wells, Anthony P. C. Brown, Alan H. Handyside*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)838-845
JournalGenetics in Medicine
Volume16
Issue number11
DOIs
Publication statusPublished - Nov 2014

Keywords

  • karyomapping
  • preimplantation genetic diagnosis
  • single-gene defect
  • single-nucleotide polymorphism
  • whole-genome amplification

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