Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro

Senthilkumar A. Natesan; Alex J. Bladon; Serdar Coskun; Wafa Qubbaj; Renata Prates; Santiago Munne; Edith Coonen; Joseph C. F. M. Dreesen; Servi J. C. Stevens; Aimee D. C. Paulussen; Sharyn E. Stock-Myer; Leeanda J. Wilton; Souraya Jaroudi; Dagan Wells; Anthony P. C. Brown; Alan H. Handyside

doi:10.1038/gim.2014.45

Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro

Senthilkumar A. Natesan, Alex J. Bladon, Serdar Coskun, Wafa Qubbaj, Renata Prates, Santiago Munne, Edith Coonen, Joseph C. F. M. Dreesen, Servi J. C. Stevens, Aimee D. C. Paulussen, Sharyn E. Stock-Myer, Leeanda J. Wilton, Souraya Jaroudi, Dagan Wells, Anthony P. C. Brown, Alan H. Handyside

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	838-845
Journal	Genetics in Medicine
Volume	16
Issue number	11
DOIs	https://doi.org/10.1038/gim.2014.45
Publication status	Published - Nov 2014

Keywords

karyomapping
preimplantation genetic diagnosis
single-gene defect
single-nucleotide polymorphism
whole-genome amplification

Access to Document

10.1038/gim.2014.45

Cite this

Natesan, S. A., Bladon, A. J., Coskun, S., Qubbaj, W., Prates, R., Munne, S., Coonen, E., Dreesen, J. C. F. M., Stevens, S. J. C., Paulussen, A. D. C., Stock-Myer, S. E., Wilton, L. J., Jaroudi, S., Wells, D., Brown, A. P. C., & Handyside, A. H. (2014). Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro. Genetics in Medicine, 16(11), 838-845. https://doi.org/10.1038/gim.2014.45

Natesan, Senthilkumar A. ; Bladon, Alex J. ; Coskun, Serdar ; Qubbaj, Wafa ; Prates, Renata ; Munne, Santiago ; Coonen, Edith ; Dreesen, Joseph C. F. M. ; Stevens, Servi J. C. ; Paulussen, Aimee D. C. ; Stock-Myer, Sharyn E. ; Wilton, Leeanda J. ; Jaroudi, Souraya ; Wells, Dagan ; Brown, Anthony P. C. ; Handyside, Alan H. / Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro. In: Genetics in Medicine. 2014 ; Vol. 16, No. 11. pp. 838-845.

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title = "Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro",

keywords = "karyomapping, preimplantation genetic diagnosis, single-gene defect, single-nucleotide polymorphism, whole-genome amplification",

author = "Natesan, {Senthilkumar A.} and Bladon, {Alex J.} and Serdar Coskun and Wafa Qubbaj and Renata Prates and Santiago Munne and Edith Coonen and Dreesen, {Joseph C. F. M.} and Stevens, {Servi J. C.} and Paulussen, {Aimee D. C.} and Stock-Myer, {Sharyn E.} and Wilton, {Leeanda J.} and Souraya Jaroudi and Dagan Wells and Brown, {Anthony P. C.} and Handyside, {Alan H.}",

year = "2014",

month = nov,

doi = "10.1038/gim.2014.45",

language = "English",

volume = "16",

pages = "838--845",

journal = "Genetics in Medicine",

issn = "1098-3600",

publisher = "Nature Publishing Group",

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Natesan, SA, Bladon, AJ, Coskun, S, Qubbaj, W, Prates, R, Munne, S, Coonen, E , Dreesen, JCFM , Stevens, SJC , Paulussen, ADC, Stock-Myer, SE, Wilton, LJ, Jaroudi, S, Wells, D, Brown, APC & Handyside, AH 2014, 'Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro', Genetics in Medicine, vol. 16, no. 11, pp. 838-845. https://doi.org/10.1038/gim.2014.45

Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro. / Natesan, Senthilkumar A.; Bladon, Alex J.; Coskun, Serdar; Qubbaj, Wafa; Prates, Renata; Munne, Santiago; Coonen, Edith ; Dreesen, Joseph C. F. M.; Stevens, Servi J. C.; Paulussen, Aimee D. C.; Stock-Myer, Sharyn E.; Wilton, Leeanda J.; Jaroudi, Souraya; Wells, Dagan; Brown, Anthony P. C.; Handyside, Alan H.

In: Genetics in Medicine, Vol. 16, No. 11, 11.2014, p. 838-845.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro

AU - Natesan, Senthilkumar A.

AU - Bladon, Alex J.

AU - Coskun, Serdar

AU - Qubbaj, Wafa

AU - Prates, Renata

AU - Munne, Santiago

AU - Coonen, Edith

AU - Dreesen, Joseph C. F. M.

AU - Stevens, Servi J. C.

AU - Paulussen, Aimee D. C.

AU - Stock-Myer, Sharyn E.

AU - Wilton, Leeanda J.

AU - Jaroudi, Souraya

AU - Wells, Dagan

AU - Brown, Anthony P. C.

AU - Handyside, Alan H.

PY - 2014/11

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KW - preimplantation genetic diagnosis

KW - single-gene defect

KW - single-nucleotide polymorphism

KW - whole-genome amplification

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DO - 10.1038/gim.2014.45

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SP - 838

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JO - Genetics in Medicine

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SN - 1098-3600

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