Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

Paul J. Hop, Rene Luijk, Lucia Daxinger, Maarten van Iterson, Koen F. Dekkers, Rick Jansen, Joyce B. J. van Meurs, Peter A. C. 't Hoen, M. Arfan Ikram, Marleen M. J. van Greevenbroek, Dorret Boomsma, P. Eline Slagboom, Jan H. Veldink, Erik W. van Zwet, Bastiaan T. Heijmans*, BIOS Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Web of Science)
Original languageEnglish
Article number220
Number of pages24
JournalGenome Biology
Volume21
Issue number1
DOIs
Publication statusPublished - 28 Aug 2020

Keywords

  • DNA methylation
  • Epigenetic regulation
  • Transcription factor
  • Chromatin
  • Genetic instrumental variable
  • Functional genomics
  • Pleiotropy
  • Causal inference
  • NETHERLANDS TWIN REGISTER
  • EMBRYONIC STEM-CELLS
  • TRANSCRIPTION FACTORS
  • INTEGRATIVE ANALYSIS
  • GENOTYPE DATA
  • SEQUENCE
  • ASSOCIATION
  • RECRUITMENT
  • CHROMATIN
  • FORMAT

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