Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3

Tingwei Guo, Gabriela M. Repetto, Donna M. McDonald McGinn, Jonathan H. Chung, Hiroko Nomaru, Christopher L. Campbell, Anna Blonska, Anne S. Bassett, Eva W. C. Chow, Elisabeth E. Mlynarski, Ann Swillen, Joris Vermeesch, Koen Devriendt, Doron Gothelf, Miri Carmel, Elena Michaelovsky, Maude Schneider, Stephan Eliez, Stylianos E. Antonarakis, Karlene ColemanAoy Tomita-Mitchell, Michael E. Mitchell, M. Cristina Digilio, Bruno Dallapiccola, Bruno Marino, Nicole Philip, Tiffany Busa, Leila Kushan-Wells, Carrie E. Bearden, Malgorzata Piotrowicz, Wanda Hawula, Amy E. Roberts, Flora Tassone, Tony J. Simon, Esther D. A. van Duin, Therese A. van Amelsvoort, Wendy R. Kates, Elaine Zackai, H. Richard Johnston, David J. Cutler, A. J. Agopian, Elizabeth Goldmuntz, Laura E. Mitchell, Tao Wang, Beverly S. Emanuel, Bernice E. Morrow*, Int 22q11 2 Consortium, Brain Behav Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numbere001690
Number of pages10
JournalCirculation : Cardiovascular Genetics
Volume10
Issue number5
DOIs
Publication statusPublished - Oct 2017

Keywords

  • chromosomes
  • DiGeorge syndrome
  • genotype
  • ivelo-cardio-facial syndrome
  • tetralogy of Fallot
  • PROTEIN-COUPLED RECEPTOR
  • CARDIO-FACIAL SYNDROME
  • DIGEORGE-SYNDROME
  • CHROMATIN ARCHITECTURE
  • CELL-DIFFERENTIATION
  • DROSOPHILA GENOME
  • GENE-EXPRESSION
  • SYNDROME REGION
  • OUTFLOW TRACT
  • HEART FIELD

Cite this

Guo, T., Repetto, G. M., McGinn, D. M. M., Chung, J. H., Nomaru, H., Campbell, C. L., Blonska, A., Bassett, A. S., Chow, E. W. C., Mlynarski, E. E., Swillen, A., Vermeesch, J., Devriendt, K., Gothelf, D., Carmel, M., Michaelovsky, E., Schneider, M., Eliez, S., Antonarakis, S. E., ... Brain Behav Consortium (2017). Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3. Circulation : Cardiovascular Genetics, 10(5), [e001690]. https://doi.org/10.1161/CIRCGENETICS.116.001690