Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

Jessica van Setten, Niek Verweij, Hamdi Mbarek, Maartje N. Niemeijer, Stella Trompet, Dan E. Arking, Jennifer A. Brody, Ilaria Gandin, Niels Grarup, Leanne M. Hall, Daiane Hemerich, Leo-Pekka Lyytikainen, Hao Mei, Martina Mueller-Nurasyid, Bram P. Prins, Antonietta Robino, Albert V. Smith, Helen R. Warren, Folkert W. Asselbergs, Dorret I. BoomsmaMark J. Caulfield, Mark Eijgelsheim, Ian Ford, Torben Hansen, Tamara B. Harris, Susan R. Heckbert, Jouke-Jan Hottenga, Annamaria Iorio, Jan A. Kors, Allan Linneberg, Peter W. MacFarlane, Thomas Meitinger, Christopher P. Nelson, Olli T. Raitakari, Claudia T. Silva Aldana, Gianfranco Sinagra, Moritz Sinner, Elsayed Z. Soliman, Monika Stoll, Andre Uitterlinden, Cornelia M. van Duijn, Melanie Waldenberger, Alvaro Alonso, Paolo Gasparini, Vilmundur Gudnason, Yalda Jamshidi, Stefan Kaab, Jorgen K. Kanters, Terho Lehtimaki, Patricia B. Munroe, Annette Peters, Nilesh J. Samani, Nona Sotoodehnia, Sheila Ulivi, James G. Wilson, Eco J. C. de Geus, J. Wouter Jukema, Bruno Stricker, Pim van der Harst, Paul I. W. de Bakker, Aaron Isaacs

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)952-962
Number of pages11
JournalEuropean Journal of Human Genetics
Volume27
Issue number6
DOIs
Publication statusPublished - Jun 2019

Keywords

  • QT INTERVAL DURATION
  • GLUCOCORTICOID-RECEPTOR
  • COMMON VARIANTS
  • HEART-RATE
  • PROTEIN
  • PHOSPHOLAMBAN
  • CONTRACTILITY
  • POLYMORPHISM
  • ANNOTATION
  • MUTATIONS

Cite this

van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikainen, L-P., Mei, H., Mueller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., ... Isaacs, A. (2019). Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics, 27(6), 952-962. https://doi.org/10.1038/s41431-018-0295-z