TY - JOUR
T1 - Genetic research on stored tissue samples from minors: a systematic review of the ethical literature
AU - Hens, K.
AU - Nys, H.
AU - Cassiman, J.J.
AU - Dierickx, K.
PY - 2009/1/1
Y1 - 2009/1/1
N2 - The potential benefits of biobank research are well known. Also, the ethical implications of genetic research on stored tissue samples are well discussed in existing literature. The inclusion of tissue samples from minors may have significant scientific value. However, this inclusion raises specific ethical questions. We have performed a systematic search of the literature and found 21 theoretical and empirical articles dealing with the issue. After review, we distilled five clusters of themes: consent, risks, benefits, return of results, and ownership. We have described the different components of these themes, as they occurred in the literature and have provided a discourse on the topic.
AB - The potential benefits of biobank research are well known. Also, the ethical implications of genetic research on stored tissue samples are well discussed in existing literature. The inclusion of tissue samples from minors may have significant scientific value. However, this inclusion raises specific ethical questions. We have performed a systematic search of the literature and found 21 theoretical and empirical articles dealing with the issue. After review, we distilled five clusters of themes: consent, risks, benefits, return of results, and ownership. We have described the different components of these themes, as they occurred in the literature and have provided a discourse on the topic.
U2 - 10.1002/ajmg.a.33032
DO - 10.1002/ajmg.a.33032
M3 - Article
C2 - 19764035
SN - 1552-4825
VL - 149A
SP - 2346
EP - 2358
JO - American Journal of Medical Genetics Part A
JF - American Journal of Medical Genetics Part A
ER -