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Generating a list of potentially important contextual factors covering randomized trials, cohorts, and measurement property studies: An OMERACT initiative

  • Max Weinbrecht-Mischkewitz*
  • , Midhat Kamal
  • , Farwa Asim
  • , Francis Guillemin
  • , Niti Goel
  • , Marieke Voshaar
  • , Annelies Boonen
  • , Dorthe Bang Berthelsen
  • , Karine Toupin-April
  • , Maria A Lopez-Olivo
  • , Victor S Sloan
  • , Maarten Boers
  • , C Allyson Jones
  • , Irene van der Horst-Bruinsma
  • , Aidan G Cashin
  • , Saurab Sharma
  • , Amye Leong
  • , Rieke Alten
  • , Beverley Shea
  • , Lyn March
  • Peter Tugwell, Robin Christensen, Sabrina Mai Nielsen, Contextual Factors Working Group
*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVES: To generate candidates for contextual factors (CFs) for each CF type (i.e., Effect Modifying Contextual Factors (EM-CFs), Outcome Influencing Contextual Factors (OI-CFs), and Measurement Affecting Contextual Factors (MA-CFs)) considered important within rheumatology. METHODS: We surveyed OMERACT working groups and conducted a Special Interest Group (SIG) session at the OMERACT 2023 meeting, where the results were reviewed, and additional CFs suggested. RESULTS: The working groups suggested 44, 49, and 21 generic EM-CFs, OI-CFs, and MA-CFs, respectively. SIG participants added 49, 44, and 55 factors, respectively. CONCLUSION: Candidate CFs were identified, next step is a consensus-based set of endorsed (important) CFs.
Original languageEnglish
Article number152370
Number of pages7
JournalSeminars in Arthritis and Rheumatism
Volume65
DOIs
Publication statusPublished - 10 Jan 2024

Keywords

  • Arthritis
  • Contextual factors
  • Effect modifiers
  • Measurement instruments
  • OMERACT
  • Prognostic factors
  • Rheumatology

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