General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial

Janine Bates*, Nick A. Francis, Patrick White, David Gillespie, Emma Thomas-Jones, Rachel Breen, Nigel Kirby, Kerry Hood, Micaela Gal, Rhiannon Phillips, Gurudutt Naik, Jochen Cals, Carl Llor, Hasse Melbye, Mandy Wootton, Evgenia Riga, Ann Cochrane, Robin Howe, Deborah Fitzsimmons, Bernadette SewellMohammed Fasihul Alam, Christopher C. Butler

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number442
Number of pages15
JournalTrials
Volume18
DOIs
Publication statusPublished - 29 Sep 2017

Keywords

  • Acute exacerbation
  • Chronic obstructive pulmonary disease
  • Primary care
  • Point-of-care test
  • C-reactive protein (CRP)
  • Near-patient testing
  • Rationalising antibiotic prescribing
  • Antibiotic resistance
  • Cost-effectiveness
  • Resistance
  • RESPIRATORY-TRACT INFECTIONS
  • MULTIPLE END-POINTS
  • STREPTOCOCCUS-PNEUMONIAE
  • SYSTEMIC CORTICOSTEROIDS
  • COPD
  • RESISTANCE
  • THERAPY
  • PROCALCITONIN
  • PREDICTORS
  • BIOMARKERS

Cite this

Bates, J., Francis, N. A., White, P., Gillespie, D., Thomas-Jones, E., Breen, R., Kirby, N., Hood, K., Gal, M., Phillips, R., Naik, G., Cals, J., Llor, C., Melbye, H., Wootton, M., Riga, E., Cochrane, A., Howe, R., Fitzsimmons, D., ... Butler, C. C. (2017). General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial. Trials, 18, [442]. https://doi.org/10.1186/s13063-017-2144-8