Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet

Sven H. Rouschop; Tanja Karl; Angela Risch; Petronella A. van Ewijk; Vera B. Schrauwen-Hinderling; Antoon Opperhuizen; Frederik J. van Schooten; Roger W. Godschalk

doi:10.1194/jlr.M092593

Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet

Sven H. Rouschop, Tanja Karl, Angela Risch, Petronella A. van Ewijk, Vera B. Schrauwen-Hinderling, Antoon Opperhuizen, Frederik J. van Schooten, Roger W. Godschalk^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1250-1259
Number of pages	10
Journal	Journal of Lipid Research
Volume	60
Issue number	7
DOIs	https://doi.org/10.1194/jlr.M092593
Publication status	Published - Jul 2019

Keywords

obesity
pregnancy
liver
microarrays
diet and dietary lipids
in utero
epigenetics
lipid metabolism
oxidative stress
development
deoxyribonucleic acid
high-fat diet
HIGH-FAT DIET
BODY-MASS INDEX
TRANSGENIC MICE
CHOLESTEROL-SYNTHESIS
LIVER-REGENERATION
ADAPTIVE RESPONSES
GLUCOSE-TOLERANCE
ACID SYNTHESIS
BINDING
PATHWAY

Access to Document

10.1194/jlr.M092593

Cite this

Rouschop, S. H., Karl, T., Risch, A., van Ewijk, P. A., Schrauwen-Hinderling, V. B., Opperhuizen, A., van Schooten, F. J., & Godschalk, R. W. (2019). Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet. Journal of Lipid Research, 60(7), 1250-1259. https://doi.org/10.1194/jlr.M092593

Rouschop, Sven H. ; Karl, Tanja ; Risch, Angela ; van Ewijk, Petronella A. ; Schrauwen-Hinderling, Vera B. ; Opperhuizen, Antoon ; van Schooten, Frederik J. ; Godschalk, Roger W. / Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet. In: Journal of Lipid Research. 2019 ; Vol. 60, No. 7. pp. 1250-1259.

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title = "Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet",

keywords = "obesity, pregnancy, liver, microarrays, diet and dietary lipids, in utero, epigenetics, lipid metabolism, oxidative stress, development, deoxyribonucleic acid, high-fat diet, HIGH-FAT DIET, BODY-MASS INDEX, TRANSGENIC MICE, CHOLESTEROL-SYNTHESIS, LIVER-REGENERATION, ADAPTIVE RESPONSES, GLUCOSE-TOLERANCE, ACID SYNTHESIS, BINDING, PATHWAY",

author = "Rouschop, {Sven H.} and Tanja Karl and Angela Risch and {van Ewijk}, {Petronella A.} and Schrauwen-Hinderling, {Vera B.} and Antoon Opperhuizen and {van Schooten}, {Frederik J.} and Godschalk, {Roger W.}",

year = "2019",

month = jul,

doi = "10.1194/jlr.M092593",

language = "English",

volume = "60",

pages = "1250--1259",

journal = "Journal of Lipid Research",

issn = "0022-2275",

publisher = "American Society for Biochemistry and Molecular Biology, Inc.",

number = "7",

}

Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet. / Rouschop, Sven H.; Karl, Tanja; Risch, Angela; van Ewijk, Petronella A.; Schrauwen-Hinderling, Vera B.; Opperhuizen, Antoon ; van Schooten, Frederik J.; Godschalk, Roger W.

In: Journal of Lipid Research, Vol. 60, No. 7, 07.2019, p. 1250-1259.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet

AU - Rouschop, Sven H.

AU - Karl, Tanja

AU - Risch, Angela

AU - van Ewijk, Petronella A.

AU - Schrauwen-Hinderling, Vera B.

AU - Opperhuizen, Antoon

AU - van Schooten, Frederik J.

AU - Godschalk, Roger W.

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KW - pregnancy

KW - liver

KW - microarrays

KW - diet and dietary lipids

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KW - epigenetics

KW - lipid metabolism

KW - oxidative stress

KW - development

KW - deoxyribonucleic acid

KW - high-fat diet

KW - HIGH-FAT DIET

KW - BODY-MASS INDEX

KW - TRANSGENIC MICE

KW - CHOLESTEROL-SYNTHESIS

KW - LIVER-REGENERATION

KW - ADAPTIVE RESPONSES

KW - GLUCOSE-TOLERANCE

KW - ACID SYNTHESIS

KW - BINDING

KW - PATHWAY

U2 - 10.1194/jlr.M092593

DO - 10.1194/jlr.M092593

M3 - Article

VL - 60

SP - 1250

EP - 1259

JO - Journal of Lipid Research

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