GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer

Alexandra J Stewart; Evert J Van Limbergen; Jean-Pierre Gerard; Ane L Appelt; Frank Verhaegen; Maaike Berbee; Te Vuong; Ciarna Brooker; Tim Rockall; Arthur Sun Myint

doi:10.1016/j.ctro.2021.12.004

GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer

Alexandra J Stewart^*, Evert J Van Limbergen, Jean-Pierre Gerard, Ane L Appelt, Frank Verhaegen, Maaike Berbee, Te Vuong, Ciarna Brooker, Tim Rockall, Arthur Sun Myint

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Purpose: To issue consensus recommendations for contact X-Ray brachytherapy (CXB) for rectal cancer covering pre-treatment evaluation, treatment, dosimetric issues and follow-up. These recommendations cover CXB in the definitive and palliative setting.

Methods: Members of GEC ESTRO with expertise in rectal CXB issued consensus-based recommendations for CXB based on literature review and clinical experience. Levels of evidence according to the Oxford Centre for Evidence based medicine guidance are presented where possible.

Results: The GEC ESTRO ACROP consensus recommendations support the use of CXB to increase the chances of clinical complete remission and cure for patients who are elderly with high surgical risk, surgically unfit or refusing surgery. For palliative treatment, the use of CXB is recommended for symptomatic relief and disease control. The use of CXB in an organ-preservation setting in surgically fit patients is recommended within the setting of a clinical trial or registry.

Conclusions: The GEC ESTRO ACROP recommendations for CXB are provided. Recommendations towards standardisation of reporting and prescription are given. Practitioners are encouraged to follow these recommendations and to develop further clinical trials to examine this treatment modality and increase the evidence base for its use. The routine collection of outcomes both clinical and patient-reported is also encouraged.

Original language	English
Pages (from-to)	15-22
Number of pages	8
Journal	Clinical and Translational Radiation Oncology
Volume	33
DOIs	https://doi.org/10.1016/j.ctro.2021.12.004
Publication status	Published - Mar 2022

Keywords

ADENOCARCINOMA
CHEMORADIATION
Consensus recommendations
Contact X-Ray brachytherapy
ELDERLY-PATIENTS
LOCAL EXCISION
ORGAN PRESERVATION
Papillon treatment
RADIATION-THERAPY
RANDOMIZED-TRIAL
Rectal cancer
SHORT-COURSE RADIOTHERAPY
SPHINCTER PRESERVATION
X-RAY BRACHYTHERAPY

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10.1016/j.ctro.2021.12.004Licence: CC BY-NC-ND

Cite this

@article{52986d9648b343088efedc1569944af6,

title = "GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer",

abstract = "Purpose: To issue consensus recommendations for contact X-Ray brachytherapy (CXB) for rectal cancer covering pre-treatment evaluation, treatment, dosimetric issues and follow-up. These recommendations cover CXB in the definitive and palliative setting.Methods: Members of GEC ESTRO with expertise in rectal CXB issued consensus-based recommendations for CXB based on literature review and clinical experience. Levels of evidence according to the Oxford Centre for Evidence based medicine guidance are presented where possible.Results: The GEC ESTRO ACROP consensus recommendations support the use of CXB to increase the chances of clinical complete remission and cure for patients who are elderly with high surgical risk, surgically unfit or refusing surgery. For palliative treatment, the use of CXB is recommended for symptomatic relief and disease control. The use of CXB in an organ-preservation setting in surgically fit patients is recommended within the setting of a clinical trial or registry.Conclusions: The GEC ESTRO ACROP recommendations for CXB are provided. Recommendations towards standardisation of reporting and prescription are given. Practitioners are encouraged to follow these recommendations and to develop further clinical trials to examine this treatment modality and increase the evidence base for its use. The routine collection of outcomes both clinical and patient-reported is also encouraged.",

keywords = "ADENOCARCINOMA, CHEMORADIATION, Consensus recommendations, Contact X-Ray brachytherapy, ELDERLY-PATIENTS, LOCAL EXCISION, ORGAN PRESERVATION, Papillon treatment, RADIATION-THERAPY, RANDOMIZED-TRIAL, Rectal cancer, SHORT-COURSE RADIOTHERAPY, SPHINCTER PRESERVATION, X-RAY BRACHYTHERAPY",

author = "Stewart, {Alexandra J} and {Van Limbergen}, {Evert J} and Jean-Pierre Gerard and Appelt, {Ane L} and Frank Verhaegen and Maaike Berbee and Te Vuong and Ciarna Brooker and Tim Rockall and {Sun Myint}, Arthur",

note = "{\textcopyright} 2021 The Authors. Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology.",

year = "2022",

month = mar,

doi = "10.1016/j.ctro.2021.12.004",

language = "English",

volume = "33",

pages = "15--22",

journal = "Clinical and Translational Radiation Oncology",

issn = "2405-6308",

publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer

AU - Stewart, Alexandra J

AU - Van Limbergen, Evert J

AU - Gerard, Jean-Pierre

AU - Appelt, Ane L

AU - Verhaegen, Frank

AU - Berbee, Maaike

AU - Vuong, Te

AU - Brooker, Ciarna

AU - Rockall, Tim

AU - Sun Myint, Arthur

PY - 2022/3

Y1 - 2022/3

N2 - Purpose: To issue consensus recommendations for contact X-Ray brachytherapy (CXB) for rectal cancer covering pre-treatment evaluation, treatment, dosimetric issues and follow-up. These recommendations cover CXB in the definitive and palliative setting.Methods: Members of GEC ESTRO with expertise in rectal CXB issued consensus-based recommendations for CXB based on literature review and clinical experience. Levels of evidence according to the Oxford Centre for Evidence based medicine guidance are presented where possible.Results: The GEC ESTRO ACROP consensus recommendations support the use of CXB to increase the chances of clinical complete remission and cure for patients who are elderly with high surgical risk, surgically unfit or refusing surgery. For palliative treatment, the use of CXB is recommended for symptomatic relief and disease control. The use of CXB in an organ-preservation setting in surgically fit patients is recommended within the setting of a clinical trial or registry.Conclusions: The GEC ESTRO ACROP recommendations for CXB are provided. Recommendations towards standardisation of reporting and prescription are given. Practitioners are encouraged to follow these recommendations and to develop further clinical trials to examine this treatment modality and increase the evidence base for its use. The routine collection of outcomes both clinical and patient-reported is also encouraged.

AB - Purpose: To issue consensus recommendations for contact X-Ray brachytherapy (CXB) for rectal cancer covering pre-treatment evaluation, treatment, dosimetric issues and follow-up. These recommendations cover CXB in the definitive and palliative setting.Methods: Members of GEC ESTRO with expertise in rectal CXB issued consensus-based recommendations for CXB based on literature review and clinical experience. Levels of evidence according to the Oxford Centre for Evidence based medicine guidance are presented where possible.Results: The GEC ESTRO ACROP consensus recommendations support the use of CXB to increase the chances of clinical complete remission and cure for patients who are elderly with high surgical risk, surgically unfit or refusing surgery. For palliative treatment, the use of CXB is recommended for symptomatic relief and disease control. The use of CXB in an organ-preservation setting in surgically fit patients is recommended within the setting of a clinical trial or registry.Conclusions: The GEC ESTRO ACROP recommendations for CXB are provided. Recommendations towards standardisation of reporting and prescription are given. Practitioners are encouraged to follow these recommendations and to develop further clinical trials to examine this treatment modality and increase the evidence base for its use. The routine collection of outcomes both clinical and patient-reported is also encouraged.

KW - ADENOCARCINOMA

KW - CHEMORADIATION

KW - Consensus recommendations

KW - Contact X-Ray brachytherapy

KW - ELDERLY-PATIENTS

KW - LOCAL EXCISION

KW - ORGAN PRESERVATION

KW - Papillon treatment

KW - RADIATION-THERAPY

KW - RANDOMIZED-TRIAL

KW - Rectal cancer

KW - SHORT-COURSE RADIOTHERAPY

KW - SPHINCTER PRESERVATION

KW - X-RAY BRACHYTHERAPY

U2 - 10.1016/j.ctro.2021.12.004

DO - 10.1016/j.ctro.2021.12.004

M3 - Article

C2 - 35243017

SN - 2405-6308

VL - 33

SP - 15

EP - 22

JO - Clinical and Translational Radiation Oncology

JF - Clinical and Translational Radiation Oncology

ER -