Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

A.M. Sailer*, M.W. de Haan, R. de Graaf, W.H. van Zwam, G.W.H. Schurink, P.J. Nelemans, J.E. Wildberger, M. Das

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


This study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).

Fusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.

Average time needed for image coregistration was 5 +/- A 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 +/- A 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 +/- A 1.96 standard deviation).

Fluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety.

Original languageEnglish
Pages (from-to)314-321
Number of pages8
JournalCardiovascular and Interventional Radiology
Issue number2
Publication statusPublished - Apr 2015


  • Multimodal imaging
  • Magnetic resonance angiography
  • Multidetector computed tomography
  • Peripheral artery disease
  • Digital subtraction angiography
  • Fluoroscopy
  • CTA


Dive into the research topics of 'Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study'. Together they form a unique fingerprint.

Cite this