From the pathophysiology of the human lung alveolus to epigenetic editing: Congress 2018 highlights from ERS Assembly 3 "Basic and Translational Science."

Marko Z Nikolić, Eva M Garrido-Martin, Flavia R Greiffo, Aurélie Fabre, Irene H Heijink, Agnes Boots, Catherine M Greene, Pieter S Hiemstra, Sabine Bartel*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Citations (Web of Science)

Abstract

The European Respiratory Society (ERS) International Congress is the largest respiratory congress and brings together leading experts in all fields of respiratory medicine and research. ERS Assembly 3 shapes the basic and translational science aspects of this congress, aiming to combine cutting-edge novel developments in basic research with novel clinical findings. In this article, we summarise a selection of the scientific highlights from the perspective of the three groups within Assembly 3. In particular, we discuss new insights into the pathophysiology of the human alveolus, novel tools in organoid development and (epi)genome editing, as well as insights from the presented abstracts on novel therapeutic targets being identified for idiopathic pulmonary fibrosis.

Original languageEnglish
Article number00194-2018
Number of pages9
JournalERJ Open Research
Volume5
Issue number2
DOIs
Publication statusPublished - 1 Apr 2019

Keywords

  • HUMAN FETAL LUNG
  • STEM-CELLS
  • DISEASE
  • MODEL
  • REGENERATION
  • CRISPR-CAS9
  • EXPRESSION
  • EPITHELIUM
  • FIBROSIS
  • REPAIR

Cite this