From the exposome to mechanistic understanding of chemical-induced adverse effects

Beate I. Escher*, Joerg Hackermuller, Tobias Polte, Stefan Scholz, Achim Aigner, Rolf Altenburger, Alexander Boehme, Stephanie K. Bopp, Werner Brack, Wibke Busch, Marc Chadeau-Hyam, Adrian Covaci, Adolf Eisentraeger, James J. Galligan, Natalia Garcia-Reyero, Thomas Hartung, Michaela Hein, Gunda Herberth, Annika Jahnke, Jos KleinjansNils Kluever, Martin Krauss, Marja Lamoree, Irina Lehmann, Till Luckenbach, Gary W. Miller, Andrea Mueller, David H. Phillips, Thorsten Reemtsma, Ulrike Rolle-Kampczyk, Gerrit Schueuermann, Benno Schwikowski, Yu-Mei Tan, Saskia Trump, Susanne Walter-Rohde, John F. Wambaugh

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)97-106
Number of pages10
JournalEnvironment International
Volume99
DOIs
Publication statusPublished - Feb 2017

Keywords

  • Exposome
  • AOP
  • Systems toxicology
  • Systems biology
  • Systems chemistry
  • Risk assessment
  • EFFECT-DIRECTED ANALYSIS
  • INTEGRATED TESTING STRATEGIES
  • ENVIRONMENTAL RISK-ASSESSMENT
  • HUMAN HAZARD CHARACTERIZATION
  • GENE-EXPRESSION DATA
  • OUTCOME PATHWAYS
  • PERFLUORINATED COMPOUNDS
  • ORGANIC MICROPOLLUTANTS
  • SYSTEMS TOXICOLOGY
  • SAFETY ASSESSMENT

Cite this

Escher, B. I., Hackermuller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Boehme, A., Bopp, S. K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisentraeger, A., Galligan, J. J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., ... Wambaugh, J. F. (2017). From the exposome to mechanistic understanding of chemical-induced adverse effects. Environment International, 99, 97-106. https://doi.org/10.1016/j.envint.2016.11.029