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Joost R. C. Lameijer*, Angela M. P. Coolen, Adri C. Voogd, Luc J. Strobbe, Marieke W. J. Louwman, Dick Venderink, Vivian C. Tjan-Heijnen, Lucien E. M. Duijm
Research output: Contribution to journal › Article › Academic › peer-review
PurposeTo determine the frequency and characteristics of contralateral, non-recalled breast abnormalities following recall at screening mammography.MethodsWe included a series of 130,338 screening mammograms performed between 1 January 2014 and 1 January 2016. During the 1-year follow-up, clinical data were collected for all recalls. Screening outcome was determined for recalled women with or without evaluation of contralateral breast abnormalities.ResultsOf 3,995 recalls (recall rate 3.1%), 129 women (3.2%) underwent assessment of a contralateral, non-recalled breast abnormality. Most lesions were detected at clinical mammography and/or breast tomosynthesis (101 women, 78.3%). The biopsy rate was similar for recalled lesions and contralateral, non-recalled lesions, but the positive predictive value of biopsy was higher for recalled lesions (p = 0.01). A comparable proportion of the recalled lesions and contralateral, non-recalled lesions were malignant (p = 0.1). The proportion of ductal carcinoma in situ was similar for both groups, as well as invasive cancer characteristics and type of surgical treatment.ConclusionsAbout 3% of recalled women underwent evaluation of contralateral, non-recalled breast lesions. Evaluation of the contralateral breast after recall is important as we found that 15.5% of contralateral, non-recalled lesions were malignant. Contralateral cancers and screen-detected cancers show similar characteristics, stage and surgical treatment.Key Points center dot 3% of recalled women underwent evaluation of contralateral, non-recalled lesions center dot One out of seven contralateral, non-recalled lesions was malignant center dot A contralateral cancer was diagnosed in 0.5% of recalls center dot Screen-detected cancers and non-recalled, contralateral cancers showed similar histological characteristics center dot Tumour stage and surgical treatment were similar for both groups
Original language | English |
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Pages (from-to) | 4205-4214 |
Number of pages | 10 |
Journal | European Radiology |
Volume | 28 |
Issue number | 10 |
DOIs | |
Publication status | Published - Oct 2018 |
Research output: Contribution to journal › Erratum / corrigendum / retractions › Academic