Four weeks' corticosteroid inhalation does not augment maximal power output in endurance athletes.

H. Kuipers, G.A. van 't Hullenaar, B.M. Pluim, S.E. Overbeek, O. De Hon, E. van Breda, L.J. van Loon

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    OBJECTIVE: To assess possible ergogenic properties of corticosteroid administration. DESIGN: A balanced, double blind, placebo-controlled design was used. PARTICIPANTS: Twenty-eight well-trained cyclists and rowers. INTERVENTION: Four weeks daily inhalation of 800 microg budesonide or placebo. Main outcome measurements: The subjects performed three incremental cycle ergometer tests until exhaustion, before and after two and four weeks of placebo or budesonide administration, to measure maximal power output (Wmax). Once a week they filled in a profile of mood state (POMS) questionnaire. RESULTS: There was no significant difference in Wmax between the placebo (376+/-25 watt) and the corticosteroid group (375+/-36 watt) during the pre-intervention test, and there were no significant changes in either group after two and four weeks of intervention. No effect of the intervention on mood state was found. CONCLUSION: Four weeks of corticosteroid or placebo inhalation in healthy, well-trained athletes did not affect maximal power output or mood state. Hence no ergogenic properties of four weeks corticosteroid administration could be demonstrated, which corroborates previous studies with short-term corticosteroid administration.
    Original languageEnglish
    Pages (from-to)568-571
    JournalBritish Journal of Sports Medicine
    Issue number11
    Publication statusPublished - 1 Jan 2008

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