Four weeks' corticosteroid inhalation does not augment maximal power output in endurance athletes.

H. Kuipers*, G.A. van 't Hullenaar, B.M. Pluim, S.E. Overbeek, O. De Hon, E. van Breda, L.J. van Loon

*Corresponding author for this work

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    OBJECTIVE: To assess possible ergogenic properties of corticosteroid administration. DESIGN: A balanced, double blind, placebo-controlled design was used. PARTICIPANTS: Twenty-eight well-trained cyclists and rowers. INTERVENTION: Four weeks daily inhalation of 800 microg budesonide or placebo. Main outcome measurements: The subjects performed three incremental cycle ergometer tests until exhaustion, before and after two and four weeks of placebo or budesonide administration, to measure maximal power output (Wmax). Once a week they filled in a profile of mood state (POMS) questionnaire. RESULTS: There was no significant difference in Wmax between the placebo (376+/-25 watt) and the corticosteroid group (375+/-36 watt) during the pre-intervention test, and there were no significant changes in either group after two and four weeks of intervention. No effect of the intervention on mood state was found. CONCLUSION: Four weeks of corticosteroid or placebo inhalation in healthy, well-trained athletes did not affect maximal power output or mood state. Hence no ergogenic properties of four weeks corticosteroid administration could be demonstrated, which corroborates previous studies with short-term corticosteroid administration.
    Original languageEnglish
    Pages (from-to)568-571
    JournalBritish Journal of Sports Medicine
    Issue number11
    Publication statusPublished - 1 Jan 2008

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