Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity

S.A. Langie, A.M. Knaapen, C.H.M.A. Ramaekers, J. Theys, J. Brun, R.W. Godschalk, F.J. van Schooten, P. Lambin, D.A. Gray, B.G. Wouters, R.K. Chiu*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Web of Science)
3 Downloads (Pure)
Original languageEnglish
Pages (from-to)852-862
Number of pages11
JournalDna Repair
Volume6
Issue number6
DOIs
Publication statusPublished - 1 Jun 2007

Keywords

  • benzo(a)pyrene
  • DNA damage tolerance
  • mutagenesis
  • translesion synthesis
  • ubiquitin
  • DNA-POLYMERASE-KAPPA
  • WHITE BLOOD-CELLS
  • DIOL EPOXIDE
  • EXCISION-REPAIR
  • TRANSLESION SYNTHESIS
  • CONJUGATING ENZYMES
  • MAMMALIAN-CELLS
  • ADDUCTS
  • PCNA
  • REPLICATION

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