Folic acid reduces doxorubicin-induced cardiomyopathy by modulating endothelial nitric oxide synthase

Yanti Octavia, Georgios Kararigas*, Martine de Boer, Ihsan Chrifi, Rinrada Kietadisorn, Melissa Swinnen, Hans Duimel, Fons K. Verheyen, Maarten M. Brandt, Daniela Fliegner, Caroline Cheng, Stefan Janssens, Dirk J. Duncker*, An L. Moens

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)3277-3287
Number of pages11
JournalJournal of Cellular and Molecular Medicine
Volume21
Issue number12
DOIs
Publication statusPublished - Dec 2017

Keywords

  • anthracycline
  • antioxidant enzyme
  • cardiotoxicity
  • free radical
  • nitric oxide
  • LEFT-VENTRICULAR DYSFUNCTION
  • CARDIAC DYSFUNCTION
  • CARDIOVASCULAR-DISEASE
  • INDUCED CARDIOTOXICITY
  • MITOCHONDRIAL-FUNCTION
  • PRESSURE-OVERLOAD
  • HEART-FAILURE
  • MORTALITY
  • PROTECTS
  • INJURY

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