Fluid resuscitation during persistent postpartum haemorrhage and maternal outcome: A nationwide cohort study

Dacia D. C. A. Henriquez, Kitty W. M. Bloemenkamp, Rosanne M. Loeff, Joost J. Zwart, Jos J. M. van Roosmalen, Jaap Jan Zwaginga, Johanna G. van der Bom*, H. J. Adriaanse, E. S. A. van den Akker, M. I. Baas, C. M. C. Bank, E. van Beek, B. A. de Boer, K. de Boer, D. M. R. van der Borden, H. A. Bremer, J. T. J. Brons, J. M. Burggraaff, H. Ceelie, H. ChonJ. L. M. Cikot, F. M. C. Delemarre, J. H. C. Diris, M. Doesburg-van Kleffens, I. M. A. van Dooren, J. L. P. van Duijnhoven, F. M. van Dunne, J. J. Duvekot, P. Engbers, M. J. W. van Ettenvan Hulst, H. Feitsma, M. A. Fouraux, M. T. M. Franssen, M. A. M. Frasa, A. J. van Gammeren, N. van Gemund, F. van der Graaf, C. J. M. de Groot, C. M. Hackeng, D. P. van der Ham, M. J. C. P. Hanssen, T. H. M. Hasaart, H. A. Hendriks, Y. M. C. Henskens, R. H. M. Peters, J. G. J. Pouwels, T. E. M. Verhagen, H. Visser, M. J. de Vries, A. C. de Wit, TeMpOH-1 study group

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Web of Science)

Abstract

Objective: To determine the association between increasing volumes of crystalloids and colloids administered before transfusion of packed red blood cells in women with persistent postpartum haemorrhage and adverse maternal outcomes.

Study design: Retrospective cohort study in the Netherlands. Women with persistent postpartum haemorrhage and known clear fluids volume for resuscitation were included. Women who received

Results: Of the 883 included women, 199 received 2 to 3 to 4 to 5 to 3 to 4 to 5 to

Conclusion: Clear fluids volume >4 L was independently associated with adverse maternal outcome in women with persistent postpartum haemorrhage. (C) 2019 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)49-56
Number of pages8
JournalEuropean Journal of Obstetrics & Gynecology and Reproductive Biology
Volume235
DOIs
Publication statusPublished - Apr 2019

Keywords

  • Blood transfusion
  • Crystalloid solutions
  • Colloids
  • Postpartum haemorrhage
  • Resuscitation
  • RED-BLOOD-CELLS
  • THROMBIN GENERATION
  • TRAUMA PATIENTS
  • ERYTHROCYTES
  • COAGULOPATHY
  • CRYSTALLOIDS
  • COLLOIDS

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