TY - JOUR
T1 - Fluid Intake and Colorectal Cancer Risk in the Netherlands Cohort Study
AU - Simons, Colinda C. J. M.
AU - Leurs, Lina J.
AU - Weijenberg, Matty P.
AU - Schouten, Leo J.
AU - Goldbohm, R. Alexandra (Sandra)
AU - van den Brandt, Piet A.
PY - 2010
Y1 - 2010
N2 - Total fluid intake, specifically water intake, has been suggested to protect against colorectal cancer. We examined the association of total fluid intake with colorectal cancer endpoints and possible effect modification by fiber intake within the Netherlands Cohort Study (N = 120,852). We also investigated intake of specific beverages. After 13.3 yr, 1,443 male and 1,040 female colorectal cancer cases with complete baseline questionnaires were available for case-cohort analyses. Multivariate analyses showed no dose-response relationship of total fluid intake and intake of specific beverages with the risk of overall colorectal, proximal, and distal colon cancer. For rectal cancer risk in men, there was a nonsignificant positive trend for total fluid intake [>1,500 vs. 6 vs.
AB - Total fluid intake, specifically water intake, has been suggested to protect against colorectal cancer. We examined the association of total fluid intake with colorectal cancer endpoints and possible effect modification by fiber intake within the Netherlands Cohort Study (N = 120,852). We also investigated intake of specific beverages. After 13.3 yr, 1,443 male and 1,040 female colorectal cancer cases with complete baseline questionnaires were available for case-cohort analyses. Multivariate analyses showed no dose-response relationship of total fluid intake and intake of specific beverages with the risk of overall colorectal, proximal, and distal colon cancer. For rectal cancer risk in men, there was a nonsignificant positive trend for total fluid intake [>1,500 vs. 6 vs.
U2 - 10.1080/01635580903407098
DO - 10.1080/01635580903407098
M3 - Article
C2 - 20358468
SN - 0163-5581
VL - 62
SP - 307
EP - 321
JO - Nutrition and Cancer-An International Journal
JF - Nutrition and Cancer-An International Journal
IS - 3
ER -