Fish and human health: an umbrella review of observational studies

J. Jurek; M. Owczarek; J. Godos; S. La Vignera; R.A. Condorelli; S. Marventano; M. Tieri; F. Ghelfi; L. Titta; A. Lafranconi; A. Gambera; E. Alonzo; S. Sciacca; S. Buscemi; S. Ray; D. Del Rio; F. Galvano; G. Grosso

doi:10.1080/09637486.2022.2090520

Fish and human health: an umbrella review of observational studies

J. Jurek, M. Owczarek, J. Godos, S. La Vignera, R.A. Condorelli, S. Marventano, M. Tieri, F. Ghelfi, L. Titta, A. Lafranconi, A. Gambera, E. Alonzo, S. Sciacca, S. Buscemi, S. Ray, D. Del Rio, F. Galvano, G. Grosso^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Fish represents one of the most important dietary sources of omega-3 polyunsaturated fatty acids, which are known to be associated with various health benefits. This study aimed to systematically review existing meta-analyses of observational studies exploring the association between fish intake and various health outcomes. A systematic search of electronic databases was conducted to retrieve a total of 63 studies. Evidence was deemed as possible for the association between higher fish intake and decreased risk of the acute coronary syndrome, liver cancer, and depression, and limited for other outcomes (including age-related macular degeneration, Alzheimer's disease, heart failure, all-cause and coronary heart disease mortality, total and ischaemic stroke) due to heterogeneity between results and potential otherwise inexplicable confounding factors. In conclusion, results from epidemiological studies support the mechanistic effects associated with omega-3 fatty acids from high fish consumption, but evidence needs to be further corroborated with more reliable results.

Original language	English
Pages (from-to)	851-860
Number of pages	10
Journal	International Journal of Food Sciences and Nutrition
Volume	73
Issue number	7
Early online date	25 Jun 2022
DOIs	https://doi.org/10.1080/09637486.2022.2090520
Publication status	Published - 3 Oct 2022

Keywords

Fish
omega-3
meta-analysis
umbrella review
evidence
non-communicable diseases
depression
mortality
cardiovascular disease
coronary heart disease
liver cancer
POLYUNSATURATED FATTY-ACIDS
DOSE-RESPONSE METAANALYSIS
COGNITIVE IMPAIRMENT RISKS
ESOPHAGEAL CANCER-RISK
COLORECTAL-CANCER
MEAT CONSUMPTION
DIETARY FACTORS
THYROID-CANCER
HEART-FAILURE
PUFA INTAKE

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Cite this

Jurek, J., Owczarek, M., Godos, J., La Vignera, S., Condorelli, R. A., Marventano, S., Tieri, M., Ghelfi, F., Titta, L., Lafranconi, A., Gambera, A., Alonzo, E., Sciacca, S., Buscemi, S., Ray, S., Del Rio, D., Galvano, F., & Grosso, G. (2022). Fish and human health: an umbrella review of observational studies. International Journal of Food Sciences and Nutrition, 73(7), 851-860. https://doi.org/10.1080/09637486.2022.2090520

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title = "Fish and human health: an umbrella review of observational studies",

abstract = "Fish represents one of the most important dietary sources of omega-3 polyunsaturated fatty acids, which are known to be associated with various health benefits. This study aimed to systematically review existing meta-analyses of observational studies exploring the association between fish intake and various health outcomes. A systematic search of electronic databases was conducted to retrieve a total of 63 studies. Evidence was deemed as possible for the association between higher fish intake and decreased risk of the acute coronary syndrome, liver cancer, and depression, and limited for other outcomes (including age-related macular degeneration, Alzheimer's disease, heart failure, all-cause and coronary heart disease mortality, total and ischaemic stroke) due to heterogeneity between results and potential otherwise inexplicable confounding factors. In conclusion, results from epidemiological studies support the mechanistic effects associated with omega-3 fatty acids from high fish consumption, but evidence needs to be further corroborated with more reliable results.",

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author = "J. Jurek and M. Owczarek and J. Godos and {La Vignera}, S. and R.A. Condorelli and S. Marventano and M. Tieri and F. Ghelfi and L. Titta and A. Lafranconi and A. Gambera and E. Alonzo and S. Sciacca and S. Buscemi and S. Ray and {Del Rio}, D. and F. Galvano and G. Grosso",

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doi = "10.1080/09637486.2022.2090520",

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Jurek, J, Owczarek, M, Godos, J, La Vignera, S, Condorelli, RA, Marventano, S, Tieri, M, Ghelfi, F, Titta, L, Lafranconi, A, Gambera, A, Alonzo, E, Sciacca, S, Buscemi, S, Ray, S, Del Rio, D, Galvano, F & Grosso, G 2022, 'Fish and human health: an umbrella review of observational studies', International Journal of Food Sciences and Nutrition, vol. 73, no. 7, pp. 851-860. https://doi.org/10.1080/09637486.2022.2090520

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T1 - Fish and human health: an umbrella review of observational studies

AU - Jurek, J.

AU - Owczarek, M.

AU - Godos, J.

AU - La Vignera, S.

AU - Condorelli, R.A.

AU - Marventano, S.

AU - Tieri, M.

AU - Ghelfi, F.

AU - Titta, L.

AU - Lafranconi, A.

AU - Gambera, A.

AU - Alonzo, E.

AU - Sciacca, S.

AU - Buscemi, S.

AU - Ray, S.

AU - Del Rio, D.

AU - Galvano, F.

AU - Grosso, G.

PY - 2022/10/3

Y1 - 2022/10/3

N2 - Fish represents one of the most important dietary sources of omega-3 polyunsaturated fatty acids, which are known to be associated with various health benefits. This study aimed to systematically review existing meta-analyses of observational studies exploring the association between fish intake and various health outcomes. A systematic search of electronic databases was conducted to retrieve a total of 63 studies. Evidence was deemed as possible for the association between higher fish intake and decreased risk of the acute coronary syndrome, liver cancer, and depression, and limited for other outcomes (including age-related macular degeneration, Alzheimer's disease, heart failure, all-cause and coronary heart disease mortality, total and ischaemic stroke) due to heterogeneity between results and potential otherwise inexplicable confounding factors. In conclusion, results from epidemiological studies support the mechanistic effects associated with omega-3 fatty acids from high fish consumption, but evidence needs to be further corroborated with more reliable results.

AB - Fish represents one of the most important dietary sources of omega-3 polyunsaturated fatty acids, which are known to be associated with various health benefits. This study aimed to systematically review existing meta-analyses of observational studies exploring the association between fish intake and various health outcomes. A systematic search of electronic databases was conducted to retrieve a total of 63 studies. Evidence was deemed as possible for the association between higher fish intake and decreased risk of the acute coronary syndrome, liver cancer, and depression, and limited for other outcomes (including age-related macular degeneration, Alzheimer's disease, heart failure, all-cause and coronary heart disease mortality, total and ischaemic stroke) due to heterogeneity between results and potential otherwise inexplicable confounding factors. In conclusion, results from epidemiological studies support the mechanistic effects associated with omega-3 fatty acids from high fish consumption, but evidence needs to be further corroborated with more reliable results.

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KW - liver cancer

KW - POLYUNSATURATED FATTY-ACIDS

KW - DOSE-RESPONSE METAANALYSIS

KW - COGNITIVE IMPAIRMENT RISKS

KW - ESOPHAGEAL CANCER-RISK

KW - COLORECTAL-CANCER

KW - MEAT CONSUMPTION

KW - DIETARY FACTORS

KW - THYROID-CANCER

KW - HEART-FAILURE

KW - PUFA INTAKE

U2 - 10.1080/09637486.2022.2090520

DO - 10.1080/09637486.2022.2090520

M3 - (Systematic) Review article

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SN - 0963-7486

VL - 73

SP - 851

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JO - International Journal of Food Sciences and Nutrition

JF - International Journal of Food Sciences and Nutrition

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