Female urothelial cell carcinoma in a failed kidney graft of a male recipient

H. J. J. de Jongh*, E. M. van Duijnhoven, A. Ruland, M. M. A. Abdul Hamid, E. J. M. Speel, K. van de Beek

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

We present a case of a male kidney transplant patient harbouring two kidney grafts of which one is functional. In the failed graft, he developed urothelial cell carcinoma with cells containing XX-chromosome, and female tumour cells were also found in the bladder. The patient underwent donor nephrectomy, was treated with epirubicin bladder instillations, and immunosuppression was tapered. Less than a year before re-transplantation a CT scan showed no abnormalities of the first graft. Transplantectomy before a second kidney transplantation is debated.

Original languageEnglish
Pages (from-to)354-356
Number of pages3
JournalNetherlands Journal of Medicine
Volume75
Issue number8
Publication statusPublished - Oct 2017

Keywords

  • Donor-derived tumour
  • kidney transplantation
  • FISH
  • cancer
  • nephrectomy
  • IN-SITU
  • IDENTIFICATION
  • ALLOGRAFT
  • BLADDER
  • ORIGIN

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