Feasibility of Four Interventions to Improve Treatment Adherence in Migrants Living with HIV in The Netherlands

Sabrina K. Been; David A. M. C. van de Vijver; Jannigje Smit; Nadine Bassant; Katalin Pogany; Sarah E. Stutterheim; Annelies Verbon

doi:10.3390/diagnostics10110980

Feasibility of Four Interventions to Improve Treatment Adherence in Migrants Living with HIV in The Netherlands

Sabrina K. Been^*, David A. M. C. van de Vijver, Jannigje Smit, Nadine Bassant, Katalin Pogany, Sarah E. Stutterheim, Annelies Verbon^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We evaluated the feasibility and efficacy of four existing interventions to improve adherence to them in migrants living with HIV (MLWH): directly administered antiretroviral therapy (DAART), group medical appointments (GMA), early detection and treatment of psychological distress, and peer support by trained MLWH. At baseline and after the interventions, socio-demographic characteristics, psychosocial variables, and data on HIV treatment adherence were collected. The two questionnaires were completed by 234/301 (78%) MLWH included at baseline. Detectable HIV RNA decreased (from 10.3 to 6.8%) as did internalized HIV-related stigma (from 15 to 14 points), and self-reported adherence increased (between 5.5 and 8.3%). DAART and GMA were not feasible interventions. Screening of psychological distress was feasible; however, follow-up diagnostic screening and linkage to psychiatric services were not. Peer support for and by MLWH was feasible. Within this small intervention group, results on HIV RNA < 400 copies/mL (decrease of 23.6%) and outpatient clinic attendance (up to 20.4% kept more appointments) were promising

Original language	English
Article number	980
Number of pages	13
Journal	Diagnostics
Volume	10
Issue number	11
DOIs	https://doi.org/10.3390/diagnostics10110980
Publication status	Published - Nov 2020

Keywords

HIV/AIDS
migrants
treatment adherence
interventions
HIGH-INCOME COUNTRIES
ANTIRETROVIRAL THERAPY
PEER SUPPORT
PSYCHOLOGIC DISTRESS
DEPRESSIVE SYMPTOMS
SOCIAL SUPPORT
ANXIETY
OUTCOMES
POPULATION
METAANALYSIS

Access to Document

10.3390/diagnostics10110980Licence: CC BY

Cite this

@article{036e18f007954a0eaa4c3ae563747a92,

title = "Feasibility of Four Interventions to Improve Treatment Adherence in Migrants Living with HIV in The Netherlands",

abstract = "We evaluated the feasibility and efficacy of four existing interventions to improve adherence to them in migrants living with HIV (MLWH): directly administered antiretroviral therapy (DAART), group medical appointments (GMA), early detection and treatment of psychological distress, and peer support by trained MLWH. At baseline and after the interventions, socio-demographic characteristics, psychosocial variables, and data on HIV treatment adherence were collected. The two questionnaires were completed by 234/301 (78%) MLWH included at baseline. Detectable HIV RNA decreased (from 10.3 to 6.8%) as did internalized HIV-related stigma (from 15 to 14 points), and self-reported adherence increased (between 5.5 and 8.3%). DAART and GMA were not feasible interventions. Screening of psychological distress was feasible; however, follow-up diagnostic screening and linkage to psychiatric services were not. Peer support for and by MLWH was feasible. Within this small intervention group, results on HIV RNA < 400 copies/mL (decrease of 23.6%) and outpatient clinic attendance (up to 20.4% kept more appointments) were promising",

keywords = "HIV/AIDS, migrants, treatment adherence, interventions, HIGH-INCOME COUNTRIES, ANTIRETROVIRAL THERAPY, PEER SUPPORT, PSYCHOLOGIC DISTRESS, DEPRESSIVE SYMPTOMS, SOCIAL SUPPORT, ANXIETY, OUTCOMES, POPULATION, METAANALYSIS",

author = "Been, {Sabrina K.} and {van de Vijver}, {David A. M. C.} and Jannigje Smit and Nadine Bassant and Katalin Pogany and Stutterheim, {Sarah E.} and Annelies Verbon",

note = "Funding Information: Funding: This study was supported by a grant from the Dutch Aids Fonds (grant number: 2011107). Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2020",

month = nov,

doi = "10.3390/diagnostics10110980",

language = "English",

volume = "10",

journal = "Diagnostics",

issn = "2075-4418",

publisher = "MDPI",

number = "11",

}

TY - JOUR

T1 - Feasibility of Four Interventions to Improve Treatment Adherence in Migrants Living with HIV in The Netherlands

AU - Been, Sabrina K.

AU - van de Vijver, David A. M. C.

AU - Smit, Jannigje

AU - Bassant, Nadine

AU - Pogany, Katalin

AU - Stutterheim, Sarah E.

AU - Verbon, Annelies

PY - 2020/11

Y1 - 2020/11

N2 - We evaluated the feasibility and efficacy of four existing interventions to improve adherence to them in migrants living with HIV (MLWH): directly administered antiretroviral therapy (DAART), group medical appointments (GMA), early detection and treatment of psychological distress, and peer support by trained MLWH. At baseline and after the interventions, socio-demographic characteristics, psychosocial variables, and data on HIV treatment adherence were collected. The two questionnaires were completed by 234/301 (78%) MLWH included at baseline. Detectable HIV RNA decreased (from 10.3 to 6.8%) as did internalized HIV-related stigma (from 15 to 14 points), and self-reported adherence increased (between 5.5 and 8.3%). DAART and GMA were not feasible interventions. Screening of psychological distress was feasible; however, follow-up diagnostic screening and linkage to psychiatric services were not. Peer support for and by MLWH was feasible. Within this small intervention group, results on HIV RNA < 400 copies/mL (decrease of 23.6%) and outpatient clinic attendance (up to 20.4% kept more appointments) were promising

AB - We evaluated the feasibility and efficacy of four existing interventions to improve adherence to them in migrants living with HIV (MLWH): directly administered antiretroviral therapy (DAART), group medical appointments (GMA), early detection and treatment of psychological distress, and peer support by trained MLWH. At baseline and after the interventions, socio-demographic characteristics, psychosocial variables, and data on HIV treatment adherence were collected. The two questionnaires were completed by 234/301 (78%) MLWH included at baseline. Detectable HIV RNA decreased (from 10.3 to 6.8%) as did internalized HIV-related stigma (from 15 to 14 points), and self-reported adherence increased (between 5.5 and 8.3%). DAART and GMA were not feasible interventions. Screening of psychological distress was feasible; however, follow-up diagnostic screening and linkage to psychiatric services were not. Peer support for and by MLWH was feasible. Within this small intervention group, results on HIV RNA < 400 copies/mL (decrease of 23.6%) and outpatient clinic attendance (up to 20.4% kept more appointments) were promising

KW - HIV/AIDS

KW - migrants

KW - treatment adherence

KW - interventions

KW - HIGH-INCOME COUNTRIES

KW - ANTIRETROVIRAL THERAPY

KW - PEER SUPPORT

KW - PSYCHOLOGIC DISTRESS

KW - DEPRESSIVE SYMPTOMS

KW - SOCIAL SUPPORT

KW - ANXIETY

KW - OUTCOMES

KW - POPULATION

KW - METAANALYSIS

U2 - 10.3390/diagnostics10110980

DO - 10.3390/diagnostics10110980

M3 - Article

C2 - 33233835

SN - 2075-4418

VL - 10

JO - Diagnostics

JF - Diagnostics

IS - 11

M1 - 980

ER -