Far space remapping by tool use: A rTMS study over the right posterior parietal cortex

G. Giglia, L. Pia, A. Folegatti, A. Puma, B. Fierro, G. Cosentino, A. Berti, F. Brighina

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3 Citations (Scopus)

Abstract

BACKGROUND: In previous studies, rTMS has been successfully employed to interfere with the right posterior parietal cortex (rPPC) inducing neglect-like behavior in healthy subjects. Several studies have shown that the use of tools can modulate the boundaries between near and far space: indeed when far space is reached by the stick, far space can be remapped as near. OBJECTIVE: The aim of the present study was to investigate whether once that rTMS on the rPPC has selectively induced neglect-like bias in the near space (but not in the far space), neglect can appears also in the far space when the subjects used a tool to perform the task. METHODS: Fifteen right-handed healthy subjects executed a line length judgment task in two different spatial positions (60 cm: near space and 120 cm: far space), with or without rPPC on-line rTMS. In the far space condition, subjects performed the perceptual task while holding or not a tool. RESULTS: During rTMS, visuospatial performance significantly shifted toward right when the task was performed in the near space and in the far space when the tool was used. No significant effect was found when rTMS was delivered in the far space condition without tool use. CONCLUSIONS: Our results demonstrate that the application of rTMS on rPPC, specifically affect the representation of near space because it caused neglect both when the subjects acted in the near space and when they acted in a far space that was remapped as near by the use of a tool.
Original languageEnglish
Pages (from-to)795-800
Number of pages6
JournalBrain stimulation
Volume8
Issue number4
Early online date30 Jan 2015
DOIs
Publication statusPublished - 30 Jan 2015

Keywords

  • Neglect
  • rTMS
  • Near space
  • Far space
  • Tool use
  • Posterior parietal cortex
  • TRANSCRANIAL MAGNETIC STIMULATION
  • LINE BISECTION JUDGMENTS
  • VISUOSPATIAL NEGLECT
  • UNILATERAL NEGLECT
  • PERIPERSONAL SPACE
  • NEURAL MECHANISMS
  • SPATIAL ATTENTION
  • DAMAGED PATIENTS
  • HEALTHY-SUBJECTS
  • BODY SCHEMA

Cite this

Giglia, G., Pia, L., Folegatti, A., Puma, A., Fierro, B., Cosentino, G., Berti, A., & Brighina, F. (2015). Far space remapping by tool use: A rTMS study over the right posterior parietal cortex. Brain stimulation, 8(4), 795-800. https://doi.org/10.1016/j.brs.2015.01.412