Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats

Arend Bonen*, Swati S. Jain, Laelie A. Snook, Xiao-Xia Han, Yuko Yoshida, Kathryn H. Buddo, James S. Lally, Elizabeth D. Pask, Sabina Paglialunga, Marie-Soleil Beaudoin, Jan F. C. Glatz, Joost J. F. P. Luiken, Ewa Harasim, David C. Wright, Adrian Chabowski, Graham P. Holloway

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2381-2391
JournalDiabetologia
Volume58
Issue number10
DOIs
Publication statusPublished - Oct 2015

Keywords

  • Ceramide
  • Diacylglycerol
  • Fatty acid oxidation
  • Glucose transport
  • GLUT4
  • Insulin resistance
  • Mitochondria
  • Muscle
  • PGC-1 alpha
  • Triacylglycerol

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