Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats

Arend Bonen, Swati S. Jain, Laelie A. Snook, Xiao-Xia Han, Yuko Yoshida, Kathryn H. Buddo, James S. Lally, Elizabeth D. Pask, Sabina Paglialunga, Marie-Soleil Beaudoin, Jan F. C. Glatz, Joost J. F. P. Luiken, Ewa Harasim, David C. Wright, Adrian Chabowski, Graham P. Holloway

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2381-2391
JournalDiabetologia
Volume58
Issue number10
DOIs
Publication statusPublished - Oct 2015

Keywords

  • Ceramide
  • Diacylglycerol
  • Fatty acid oxidation
  • Glucose transport
  • GLUT4
  • Insulin resistance
  • Mitochondria
  • Muscle
  • PGC-1 alpha
  • Triacylglycerol

Cite this

Bonen, A., Jain, S. S., Snook, L. A., Han, X-X., Yoshida, Y., Buddo, K. H., Lally, J. S., Pask, E. D., Paglialunga, S., Beaudoin, M-S., Glatz, J. F. C., Luiken, J. J. F. P., Harasim, E., Wright, D. C., Chabowski, A., & Holloway, G. P. (2015). Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats. Diabetologia, 58(10), 2381-2391. https://doi.org/10.1007/s00125-015-3691-8