Abstract
The field of extracellular vesicles (EV) is rapidly expanding, also within cardiovascular diseases. Besides their exciting roles in cell-to-cell communication, EV have the potential to serve as excellent biomarkers, since their counts, content, and origin might provide useful information about the pathophysiology of cardiovascular disorders. Various studies have already indicated associations of EV counts and content with cardiovascular diseases. However, EV research is complicated by several factors, most notably the small size of EV. In this review, the advantages and drawbacks of EV-related methods and applications as biomarkers are highlighted.
Original language | English |
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Article number | 113 |
Number of pages | 9 |
Journal | Frontiers in Cardiovascular Medicine |
Volume | 5 |
DOIs | |
Publication status | Published - 22 Aug 2018 |
Keywords
- microparticle
- atherosclerosis
- vascular remodeling
- diagnostic
- platelet
- endothelial cell
- monocyte
- CIRCULATING ENDOTHELIAL MICROPARTICLES
- PLATELET-DERIVED MICROPARTICLES
- NANOPARTICLE TRACKING ANALYSIS
- MYOCARDIAL-INFARCTION PATIENTS
- ACUTE CORONARY SYNDROMES
- FLOW-CYTOMETRY
- TISSUE FACTOR
- SUBCLINICAL ATHEROSCLEROSIS
- VENOUS THROMBOEMBOLISM
- MATRIX VESICLES