External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia

S.M. van Kuijk; D.H. Delahaije; C. Dirksen; H.C. Scheepers; M.E. Spaanderman; W. Ganzevoort; J.J. Duvekot; M.A. Oudijk; M.G. van Pampus; P. von Dadelszen; L.L. Peeters; the PreCare study group; L.J. Smits

doi:10.3109/10641955.2013.872253

External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia

S.M. van Kuijk^*, D.H. Delahaije, C. Dirksen, H.C. Scheepers, M.E. Spaanderman, W. Ganzevoort, J.J. Duvekot, M.A. Oudijk, M.G. van Pampus, P. von Dadelszen, L.L. Peeters, the PreCare study group, L.J. Smits

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Objective: To validate a previously published prediction model for recurrent early-onset preeclampsia (PE). Methods: We included 229 pregnant women with a history of early-onset PE and computed their risk using the prediction model, compared the predicted risk to their pregnancy outcomes and assessed performance of the model. Results: Early-onset PE recurred in 6.6% of participants. The area under the receiver operating characteristic curve was 59% (95% CI: 45-73). The model created groups that were only moderately different in terms of their risk. Conclusions: The model's discriminate ability was poor and predictive performance insufficient to classify women into relevant risk groups.

Original language	English
Pages (from-to)	265-276
Number of pages	12
Journal	Hypertension in Pregnancy
Volume	33
Issue number	3
DOIs	https://doi.org/10.3109/10641955.2013.872253
Publication status	Published - Aug 2014

Keywords

Early-onset
External validation
Prediction
Preeclampsia
Recurrence
LOW-PLASMA-VOLUME
HYPERTENSIVE DISORDER
1ST PREGNANCY
RISK
WOMEN
DIAGNOSIS
DELIVERY
COHORT

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van Kuijk, S. M., Delahaije, D. H., Dirksen, C., Scheepers, H. C., Spaanderman, M. E., Ganzevoort, W., Duvekot, J. J., Oudijk, M. A., van Pampus, M. G., von Dadelszen, P., Peeters, L. L., PreCare study group, T., & Smits, L. J. (2014). External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia. Hypertension in Pregnancy, 33(3), 265-276. https://doi.org/10.3109/10641955.2013.872253

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title = "External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia",

abstract = "Objective: To validate a previously published prediction model for recurrent early-onset preeclampsia (PE). Methods: We included 229 pregnant women with a history of early-onset PE and computed their risk using the prediction model, compared the predicted risk to their pregnancy outcomes and assessed performance of the model. Results: Early-onset PE recurred in 6.6% of participants. The area under the receiver operating characteristic curve was 59% (95% CI: 45-73). The model created groups that were only moderately different in terms of their risk. Conclusions: The model's discriminate ability was poor and predictive performance insufficient to classify women into relevant risk groups.",

keywords = "Early-onset, External validation, Prediction, Preeclampsia, Recurrence, LOW-PLASMA-VOLUME, HYPERTENSIVE DISORDER, 1ST PREGNANCY, RISK, WOMEN, DIAGNOSIS, DELIVERY, COHORT",

author = "{van Kuijk}, S.M. and D.H. Delahaije and C. Dirksen and H.C. Scheepers and M.E. Spaanderman and W. Ganzevoort and J.J. Duvekot and M.A. Oudijk and {van Pampus}, M.G. and {von Dadelszen}, P. and L.L. Peeters and {PreCare study group}, the and L.J. Smits",

year = "2014",

month = aug,

doi = "10.3109/10641955.2013.872253",

language = "English",

volume = "33",

pages = "265--276",

journal = "Hypertension in Pregnancy",

issn = "1064-1955",

publisher = "Informa Healthcare",

number = "3",

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van Kuijk, SM, Delahaije, DH, Dirksen, C, Scheepers, HC, Spaanderman, ME, Ganzevoort, W, Duvekot, JJ, Oudijk, MA, van Pampus, MG, von Dadelszen, P, Peeters, LL, PreCare study group, T & Smits, LJ 2014, 'External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia', Hypertension in Pregnancy, vol. 33, no. 3, pp. 265-276. https://doi.org/10.3109/10641955.2013.872253

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T1 - External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia

AU - van Kuijk, S.M.

AU - Delahaije, D.H.

AU - Dirksen, C.

AU - Scheepers, H.C.

AU - Spaanderman, M.E.

AU - Ganzevoort, W.

AU - Duvekot, J.J.

AU - Oudijk, M.A.

AU - van Pampus, M.G.

AU - von Dadelszen, P.

AU - Peeters, L.L.

AU - PreCare study group, the

AU - Smits, L.J.

PY - 2014/8

Y1 - 2014/8

N2 - Objective: To validate a previously published prediction model for recurrent early-onset preeclampsia (PE). Methods: We included 229 pregnant women with a history of early-onset PE and computed their risk using the prediction model, compared the predicted risk to their pregnancy outcomes and assessed performance of the model. Results: Early-onset PE recurred in 6.6% of participants. The area under the receiver operating characteristic curve was 59% (95% CI: 45-73). The model created groups that were only moderately different in terms of their risk. Conclusions: The model's discriminate ability was poor and predictive performance insufficient to classify women into relevant risk groups.

AB - Objective: To validate a previously published prediction model for recurrent early-onset preeclampsia (PE). Methods: We included 229 pregnant women with a history of early-onset PE and computed their risk using the prediction model, compared the predicted risk to their pregnancy outcomes and assessed performance of the model. Results: Early-onset PE recurred in 6.6% of participants. The area under the receiver operating characteristic curve was 59% (95% CI: 45-73). The model created groups that were only moderately different in terms of their risk. Conclusions: The model's discriminate ability was poor and predictive performance insufficient to classify women into relevant risk groups.

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KW - External validation

KW - Prediction

KW - Preeclampsia

KW - Recurrence

KW - LOW-PLASMA-VOLUME

KW - HYPERTENSIVE DISORDER

KW - 1ST PREGNANCY

KW - RISK

KW - WOMEN

KW - DIAGNOSIS

KW - DELIVERY

KW - COHORT

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DO - 10.3109/10641955.2013.872253

M3 - Article

C2 - 24392844

SN - 1064-1955

VL - 33

SP - 265

EP - 276

JO - Hypertension in Pregnancy

JF - Hypertension in Pregnancy

IS - 3

ER -

External validation of a model for periconceptional prediction of recurrent early-onset preeclampsia

Abstract

Keywords

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