Exploring the use of silica sands and calcite from natural deposits to prepare bioactive glasses

Lizette Morejon Alonso; Jose Angel Delgado Garcia-Menocal; Maite Garcia-Valles; Salvador Martinez Manent; Elizabeth R. Balmayor; Martijn van Griensven

doi:10.3139/146.111716

Exploring the use of silica sands and calcite from natural deposits to prepare bioactive glasses

Lizette Morejon Alonso^*, Jose Angel Delgado Garcia-Menocal, Maite Garcia-Valles, Salvador Martinez Manent, Elizabeth R. Balmayor, Martijn van Griensven

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Nowadays bioactive glasses represent one of the most successful bioceramics used for bone tissue restorations. In this work, three types of silica sands (White, Yellow and Gray Sands) and calcite from Cuban natural deposits were employed to synthesize glasses from the system SiO2-CaO-Na2O. The ions released from glasses were evaluated through in vitro tests in Tris-HCl and in simulated body fluids. All sands had purity around 99.2% of SiO2 and contained traces (ppm) of Zr, Cr, Ba, Ce and Sr ions, while calcite raw material had traces of Sr, Cr, Zr, Ce and Zn. All glasses induced a pH change in Tris-HCl from 7.4 to 9 after 24 h; they had similar ion-release behavior in the in vitro solutions tested and showed a significant bioactive performance after 5 h. This work illustrates the potentialities of the use of natural resources to develop medical products when recognized trademark materials are not available.

Original language	English
Pages (from-to)	333-342
Number of pages	10
Journal	International Journal of Materials Research
Volume	110
Issue number	4
DOIs	https://doi.org/10.3139/146.111716
Publication status	Published - Apr 2019
Externally published	Yes
Event	7th International Congress of Biomaterials (BIOMAT) - Havana, Cuba Duration: 14 Mar 2018 → 16 Mar 2018

Keywords

Bioactive glasses
Natural raw sources
Bioactivity
Silica sands
RESOURCE UTILIZATION
CERAMICS

Access to Document

10.3139/146.111716

Cite this

@article{9ee29605c1784810b32b7dad2eb7dcd6,

title = "Exploring the use of silica sands and calcite from natural deposits to prepare bioactive glasses",

abstract = "Nowadays bioactive glasses represent one of the most successful bioceramics used for bone tissue restorations. In this work, three types of silica sands (White, Yellow and Gray Sands) and calcite from Cuban natural deposits were employed to synthesize glasses from the system SiO2-CaO-Na2O. The ions released from glasses were evaluated through in vitro tests in Tris-HCl and in simulated body fluids. All sands had purity around 99.2% of SiO2 and contained traces (ppm) of Zr, Cr, Ba, Ce and Sr ions, while calcite raw material had traces of Sr, Cr, Zr, Ce and Zn. All glasses induced a pH change in Tris-HCl from 7.4 to 9 after 24 h; they had similar ion-release behavior in the in vitro solutions tested and showed a significant bioactive performance after 5 h. This work illustrates the potentialities of the use of natural resources to develop medical products when recognized trademark materials are not available.",

keywords = "Bioactive glasses, Natural raw sources, Bioactivity, Silica sands, RESOURCE UTILIZATION, CERAMICS",

author = "{Morejon Alonso}, Lizette and {Delgado Garcia-Menocal}, {Jose Angel} and Maite Garcia-Valles and {Martinez Manent}, Salvador and Balmayor, {Elizabeth R.} and {van Griensven}, Martijn",

year = "2019",

month = apr,

doi = "10.3139/146.111716",

language = "English",

volume = "110",

pages = "333--342",

journal = "International Journal of Materials Research",

issn = "1862-5282",

publisher = "Carl Hanser Verlag GmbH & Co. KG",

number = "4",

note = "7th International Congress of Biomaterials (BIOMAT) ; Conference date: 14-03-2018 Through 16-03-2018",

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TY - JOUR

T1 - Exploring the use of silica sands and calcite from natural deposits to prepare bioactive glasses

AU - Morejon Alonso, Lizette

AU - Delgado Garcia-Menocal, Jose Angel

AU - Garcia-Valles, Maite

AU - Martinez Manent, Salvador

AU - Balmayor, Elizabeth R.

AU - van Griensven, Martijn

PY - 2019/4

Y1 - 2019/4

N2 - Nowadays bioactive glasses represent one of the most successful bioceramics used for bone tissue restorations. In this work, three types of silica sands (White, Yellow and Gray Sands) and calcite from Cuban natural deposits were employed to synthesize glasses from the system SiO2-CaO-Na2O. The ions released from glasses were evaluated through in vitro tests in Tris-HCl and in simulated body fluids. All sands had purity around 99.2% of SiO2 and contained traces (ppm) of Zr, Cr, Ba, Ce and Sr ions, while calcite raw material had traces of Sr, Cr, Zr, Ce and Zn. All glasses induced a pH change in Tris-HCl from 7.4 to 9 after 24 h; they had similar ion-release behavior in the in vitro solutions tested and showed a significant bioactive performance after 5 h. This work illustrates the potentialities of the use of natural resources to develop medical products when recognized trademark materials are not available.

AB - Nowadays bioactive glasses represent one of the most successful bioceramics used for bone tissue restorations. In this work, three types of silica sands (White, Yellow and Gray Sands) and calcite from Cuban natural deposits were employed to synthesize glasses from the system SiO2-CaO-Na2O. The ions released from glasses were evaluated through in vitro tests in Tris-HCl and in simulated body fluids. All sands had purity around 99.2% of SiO2 and contained traces (ppm) of Zr, Cr, Ba, Ce and Sr ions, while calcite raw material had traces of Sr, Cr, Zr, Ce and Zn. All glasses induced a pH change in Tris-HCl from 7.4 to 9 after 24 h; they had similar ion-release behavior in the in vitro solutions tested and showed a significant bioactive performance after 5 h. This work illustrates the potentialities of the use of natural resources to develop medical products when recognized trademark materials are not available.

KW - Bioactive glasses

KW - Natural raw sources

KW - Bioactivity

KW - Silica sands

KW - RESOURCE UTILIZATION

KW - CERAMICS

U2 - 10.3139/146.111716

DO - 10.3139/146.111716

M3 - Article

VL - 110

SP - 333

EP - 342

JO - International Journal of Materials Research

JF - International Journal of Materials Research

SN - 1862-5282

IS - 4

T2 - 7th International Congress of Biomaterials (BIOMAT)

Y2 - 14 March 2018 through 16 March 2018

ER -