Exploring the association of dairy product intake with the fatty acids C15:0 and C17:0 measured from dried blood spots in a multipopulation cohort: Findings from the Food4Me study

Viviana Albani, Carlos Celis-Morales, Cyril F. M. Marsaux, Hannah Forster, Clare B. O'Donovan, Clara Woolhead, Anna L. Macready, Rosalind Fallaize, Santiago Navas-Carretero, Rodrigo San-Cristobal, Silvia Kolossa, Christina Mavrogianni, Christina P. Lambrinou, George Moschonis, Magdalena Godlewska, Agnieszka Surwillo, Thomas E. Gundersen, Siv E. Kaland, Yannis Manios, Iwona TraczykChristian A. Drevon, Eileen R. Gibney, Marianne C. Walsh, J. Alfredo Martinez, Wim H. M. Saris, Hannelore Daniel, Julie A. Lovegrove, Michael J. Gibney, Ashley J. Adamson, John C. Mathers, Lorraine Brennan*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


ScopeThe use of biomarkers in the objective assessment of dietary intake is a high priority in nutrition research. The aim of this study was to examine pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) as biomarkers of dairy foods intake. Methods and resultsThe data used in the present study were obtained as part of the Food4me Study. Estimates of C15:0 and C17:0 from dried blood spots and intakes of dairy from a Food Frequency Questionnaire were obtained from participants (n = 1180) across seven countries. Regression analyses were used to explore associations of biomarkers with dairy intake levels and receiver operating characteristic analyses were used to evaluate the fatty acids. Significant positive associations were found between C15:0 and total intakes of high-fat dairy products. C15:0 showed good ability to distinguish between low and high consumers of high-fat dairy products. ConclusionC15:0 can be used as a biomarker of high-fat dairy intake and of specific high-fat dairy products. Both C15:0 and C17:0 performed poorly for total dairy intake highlighting the need for caution when using these in epidemiological studies.
Original languageEnglish
Pages (from-to)834-845
JournalMolecular Nutrition & Food Research
Issue number4
Publication statusPublished - Apr 2016


  • Biomarkers
  • Dairy intake
  • Dried blood spots
  • Heptadecanoic acid
  • Pentadecanoic acid

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