Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells

B. Verbelen, T. Girardi, S.O. Sulima, S. Vereecke, P. Verstraete, J. Verbeeck, J. Royaert, S. Cinque, L. Montanaro, M. Penzo, M. Imbrechts, N. Geukens, T. Geuens, K. Dierckx, D. Pepe, K. Kampen, K. De Keersmaecker*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)100-114
Number of pages15
JournalEngineering in Life Sciences
Volume22
Issue number2
Early online date14 Jan 2022
DOIs
Publication statusPublished - Feb 2022

Keywords

  • genome engineering
  • recombinant protein production
  • ribosomal protein mutation
  • RPL10
  • GENE KNOCKOUT
  • CHO-CELLS
  • NUCLEASE

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