EVP-6124, a novel and selective alpha 7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of alpha 7 nicotinic acetylcholine receptors

Jos Prickaerts*, Nick P. van Goethem*, Richard Chesworth, Gideon Shapiro*, Frank G. Boess*, Christoph Methfessel*, Olga A. H. Reneerkens*, Dorothy G. Flood*, Dana Hilt*, Maria Gawryl*, Sonia Bertrand*, Daniel Bertrand*, Gerhard Koenig*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1099-1110
JournalNeuropharmacology
Volume62
Issue number2
DOIs
Publication statusPublished - Feb 2012

Keywords

  • alpha 7 nAChR
  • Object recognition task
  • Memory
  • Partial agonist
  • Novel mechanism of action
  • Acetylcholine esterase inhibitor

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