EVP-6124, a novel and selective alpha 7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of alpha 7 nicotinic acetylcholine receptors

Jos Prickaerts, Nick P. van Goethem, Richard Chesworth, Gideon Shapiro, Frank G. Boess, Christoph Methfessel, Olga A. H. Reneerkens, Dorothy G. Flood, Dana Hilt, Maria Gawryl, Sonia Bertrand, Daniel Bertrand, Gerhard Koenig

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1099-1110
JournalNeuropharmacology
Volume62
Issue number2
DOIs
Publication statusPublished - Feb 2012

Keywords

  • alpha 7 nAChR
  • Object recognition task
  • Memory
  • Partial agonist
  • Novel mechanism of action
  • Acetylcholine esterase inhibitor

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