Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

Panagiotis Georgiadis; Irene Liampa; Dennie G. Hebels; Julian Krauskopf; Aristotelis Chatziioannou; Ioannis Valavanis; Theo M. C. M. de Kok; Jos C. S. Kleinjans; Ingvar A. Bergdahl; Beatrice Melin; Florentin Spaeth; Domenico Palli; R. C. H. Vermeulen; J. Vlaanderen; Marc Chadeau-Hyam; Paolo Vineis; Soterios A. Kyrtopoulos; EnviroGenomarkers Consortium

doi:10.1186/s12864-017-4117-4

Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

Panagiotis Georgiadis, Irene Liampa, Dennie G. Hebels, Julian Krauskopf, Aristotelis Chatziioannou, Ioannis Valavanis, Theo M. C. M. de Kok, Jos C. S. Kleinjans, Ingvar A. Bergdahl, Beatrice Melin, Florentin Spaeth, Domenico Palli, R. C. H. Vermeulen, J. Vlaanderen, Marc Chadeau-Hyam, Paolo Vineis, Soterios A. Kyrtopoulos^*, EnviroGenomarkers Consortium

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	728
Number of pages	15
Journal	BMC Genomics
Volume	18
DOIs	https://doi.org/10.1186/s12864-017-4117-4
Publication status	Published - 13 Sep 2017

Keywords

Epigenomics
Transcriptomics
miRNA
Biomarkers of risk
Molecular epidemiology
Prospective cohort
DISEASE PROGRESSION
RISK
CLL
FOXP1
RECEPTORS
LYMPHOMAS
DYNAMICS

Cite this

Georgiadis, P., Liampa, I., Hebels, D. G., Krauskopf, J., Chatziioannou, A., Valavanis, I., de Kok, T. M. C. M., Kleinjans, J. C. S., Bergdahl, I. A., Melin, B., Spaeth, F., Palli, D., Vermeulen, R. C. H., Vlaanderen, J., Chadeau-Hyam, M., Vineis, P., Kyrtopoulos, S. A., & EnviroGenomarkers Consortium (2017). Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis. BMC Genomics, 18, [728]. https://doi.org/10.1186/s12864-017-4117-4

Georgiadis, Panagiotis ; Liampa, Irene ; Hebels, Dennie G. ; Krauskopf, Julian ; Chatziioannou, Aristotelis ; Valavanis, Ioannis ; de Kok, Theo M. C. M. ; Kleinjans, Jos C. S. ; Bergdahl, Ingvar A. ; Melin, Beatrice ; Spaeth, Florentin ; Palli, Domenico ; Vermeulen, R. C. H. ; Vlaanderen, J. ; Chadeau-Hyam, Marc ; Vineis, Paolo ; Kyrtopoulos, Soterios A. ; EnviroGenomarkers Consortium. / Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis. In: BMC Genomics. 2017 ; Vol. 18.

@article{2c79d90c9b114fdfaf18fb191c684019,

title = "Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis",

keywords = "Epigenomics, Transcriptomics, miRNA, Biomarkers of risk, Molecular epidemiology, Prospective cohort, DISEASE PROGRESSION, RISK, CLL, FOXP1, RECEPTORS, LYMPHOMAS, DYNAMICS",

author = "Panagiotis Georgiadis and Irene Liampa and Hebels, {Dennie G.} and Julian Krauskopf and Aristotelis Chatziioannou and Ioannis Valavanis and {de Kok}, {Theo M. C. M.} and Kleinjans, {Jos C. S.} and Bergdahl, {Ingvar A.} and Beatrice Melin and Florentin Spaeth and Domenico Palli and Vermeulen, {R. C. H.} and J. Vlaanderen and Marc Chadeau-Hyam and Paolo Vineis and Kyrtopoulos, {Soterios A.} and {EnviroGenomarkers Consortium}",

year = "2017",

month = sep,

day = "13",

doi = "10.1186/s12864-017-4117-4",

language = "English",

volume = "18",

journal = "BMC Genomics",

issn = "1471-2164",

publisher = "BioMed Central Ltd",

}

Georgiadis, P, Liampa, I, Hebels, DG , Krauskopf, J, Chatziioannou, A, Valavanis, I, de Kok, TMCM , Kleinjans, JCS, Bergdahl, IA, Melin, B, Spaeth, F, Palli, D, Vermeulen, RCH, Vlaanderen, J, Chadeau-Hyam, M, Vineis, P, Kyrtopoulos, SA & EnviroGenomarkers Consortium 2017, 'Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis', BMC Genomics, vol. 18, 728. https://doi.org/10.1186/s12864-017-4117-4

Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis. / Georgiadis, Panagiotis; Liampa, Irene; Hebels, Dennie G.; Krauskopf, Julian; Chatziioannou, Aristotelis; Valavanis, Ioannis; de Kok, Theo M. C. M.; Kleinjans, Jos C. S.; Bergdahl, Ingvar A.; Melin, Beatrice; Spaeth, Florentin; Palli, Domenico; Vermeulen, R. C. H.; Vlaanderen, J.; Chadeau-Hyam, Marc; Vineis, Paolo; Kyrtopoulos, Soterios A.; EnviroGenomarkers Consortium.

In: BMC Genomics, Vol. 18, 728, 13.09.2017.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

AU - Georgiadis, Panagiotis

AU - Liampa, Irene

AU - Hebels, Dennie G.

AU - Krauskopf, Julian

AU - Chatziioannou, Aristotelis

AU - Valavanis, Ioannis

AU - de Kok, Theo M. C. M.

AU - Kleinjans, Jos C. S.

AU - Bergdahl, Ingvar A.

AU - Melin, Beatrice

AU - Spaeth, Florentin

AU - Palli, Domenico

AU - Vermeulen, R. C. H.

AU - Vlaanderen, J.

AU - Chadeau-Hyam, Marc

AU - Vineis, Paolo

AU - Kyrtopoulos, Soterios A.

AU - EnviroGenomarkers Consortium

PY - 2017/9/13

Y1 - 2017/9/13

KW - Epigenomics

KW - Transcriptomics

KW - miRNA

KW - Biomarkers of risk

KW - Molecular epidemiology

KW - Prospective cohort

KW - DISEASE PROGRESSION

KW - RISK

KW - CLL

KW - FOXP1

KW - RECEPTORS

KW - LYMPHOMAS

KW - DYNAMICS

U2 - 10.1186/s12864-017-4117-4

DO - 10.1186/s12864-017-4117-4

M3 - Article

VL - 18

JO - BMC Genomics

JF - BMC Genomics

SN - 1471-2164

M1 - 728

ER -

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10.1186/s12864-017-4117-4