Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

Panagiotis Georgiadis, Irene Liampa, Dennie G. Hebels, Julian Krauskopf, Aristotelis Chatziioannou, Ioannis Valavanis, Theo M. C. M. de Kok, Jos C. S. Kleinjans, Ingvar A. Bergdahl, Beatrice Melin, Florentin Spaeth, Domenico Palli, R. C. H. Vermeulen, J. Vlaanderen, Marc Chadeau-Hyam, Paolo Vineis, Soterios A. Kyrtopoulos*, EnviroGenomarkers Consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number728
Number of pages15
JournalBMC Genomics
Volume18
DOIs
Publication statusPublished - 13 Sep 2017

Keywords

  • Epigenomics
  • Transcriptomics
  • miRNA
  • Biomarkers of risk
  • Molecular epidemiology
  • Prospective cohort
  • DISEASE PROGRESSION
  • RISK
  • CLL
  • FOXP1
  • RECEPTORS
  • LYMPHOMAS
  • DYNAMICS

Cite this

Georgiadis, P., Liampa, I., Hebels, D. G., Krauskopf, J., Chatziioannou, A., Valavanis, I., de Kok, T. M. C. M., Kleinjans, J. C. S., Bergdahl, I. A., Melin, B., Spaeth, F., Palli, D., Vermeulen, R. C. H., Vlaanderen, J., Chadeau-Hyam, M., Vineis, P., Kyrtopoulos, S. A., & EnviroGenomarkers Consortium (2017). Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis. BMC Genomics, 18, [728]. https://doi.org/10.1186/s12864-017-4117-4