TY - JOUR
T1 - Everyday Lives of Middle-Aged Persons with Multimorbidity
T2 - A Mixed Methods Systematic Review
AU - González-González, Ana Isabel
AU - Brünn, Robin
AU - Nothacker, Julia
AU - Schwarz, Christine
AU - Nury, Edris
AU - Dinh, Truc Sophia
AU - Brueckle, Maria-Sophie
AU - Dieckelmann, Mirjam
AU - Müller, Beate Sigrid
AU - van den Akker, Marjan
N1 - Funding Information:
Funding: This research was funded by Stiftung Gesundheitswissen, grant number LW03–20.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/1
Y1 - 2022/1
N2 - The healthcare burden of patients with multimorbidity may negatively affect their family lives, leisure time and professional activities. This mixed methods systematic review synthesizes studies to assess how multimorbidity affects the everyday lives of middle-aged persons, and identifies skills and resources that may help them overcome that burden. Two independent reviewers screened title/abstracts/full texts in seven databases, extracted data and used the Mixed Methods Appraisal Tool (MMAT) to assess risk of bias (RoB). We synthesized findings from 44 studies (49,519 patients) narratively and, where possible, quantitatively. Over half the studies provided insufficient information to assess representativeness or response bias. Two studies assessed global functioning, 15 examined physical functioning, 18 psychosocial functioning and 28 work functioning. Nineteen studies explored skills and resources that help people cope with multimorbidity. Middle-aged persons with multimorbidity have greater impairment in global, physical and psychosocial functioning, as well as lower employment rates and work productivity, than those without. Certain skills and resources help them cope with their everyday lives. To provide holistic and dynamic health care plans that meet the needs of middle-aged persons, health professionals need greater understanding of the experience of coping with multimorbidity and the associated healthcare burden.
AB - The healthcare burden of patients with multimorbidity may negatively affect their family lives, leisure time and professional activities. This mixed methods systematic review synthesizes studies to assess how multimorbidity affects the everyday lives of middle-aged persons, and identifies skills and resources that may help them overcome that burden. Two independent reviewers screened title/abstracts/full texts in seven databases, extracted data and used the Mixed Methods Appraisal Tool (MMAT) to assess risk of bias (RoB). We synthesized findings from 44 studies (49,519 patients) narratively and, where possible, quantitatively. Over half the studies provided insufficient information to assess representativeness or response bias. Two studies assessed global functioning, 15 examined physical functioning, 18 psychosocial functioning and 28 work functioning. Nineteen studies explored skills and resources that help people cope with multimorbidity. Middle-aged persons with multimorbidity have greater impairment in global, physical and psychosocial functioning, as well as lower employment rates and work productivity, than those without. Certain skills and resources help them cope with their everyday lives. To provide holistic and dynamic health care plans that meet the needs of middle-aged persons, health professionals need greater understanding of the experience of coping with multimorbidity and the associated healthcare burden.
KW - ALCOHOL DEPENDENCE
KW - Adaptation, Psychological
KW - Bias
KW - COMORBID CONDITIONS
KW - Delivery of Health Care
KW - GENERALIZED ANXIETY DISORDER
KW - Health Personnel
KW - Humans
KW - LABOR-FORCE PARTICIPATION
KW - MAJOR DEPRESSION
KW - MULTIPLE CHRONIC CONDITIONS
KW - Middle Aged
KW - Multimorbidity
KW - POSTTRAUMATIC-STRESS-DISORDER
KW - QUALITY-OF-LIFE
KW - SELF-MANAGEMENT
KW - SUPPORTIVE CARE NEEDS
KW - coping resources
KW - coping skills
KW - everyday life
KW - middle-aged
KW - multimorbidity
KW - systematic review
U2 - 10.3390/ijerph19010006
DO - 10.3390/ijerph19010006
M3 - (Systematic) Review article
C2 - 35010264
SN - 1660-4601
VL - 19
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 1
M1 - 6
ER -