Evaluating Dorsal Root Ganglion Stimulation in a Prospective Dutch Cohort

Frank J. P. M. Huygen*, Liong Liem, Harold Nijhuis, William Cusack, Jeffery Kramer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Web of Science)

Abstract

ObjectivesDorsal root ganglion (DRG) stimulation is a recent neuromodulation option that has delivered safe, effective pain relief for a number of etiologies. This prospective observational study was intended to establish the effectiveness of this treatment in a typical real-world clinical context.

Materials and MethodsParticipants with chronic, intractable pain of the trunk or lower limbs were recruited from multiple pain clinics in the Netherlands. Subjects were trialed and implanted with DRG stimulation systems. Pain, function, mood, and quality of life, ratings were collected through 12 months postimplant.

ResultsOf the 66 subjects enrolled, failed back surgery syndrome, peripheral nerve injury, and complex regional pain syndrome formed the largest etiologies. Permanent implants were placed in 86.2% subjects (56/65). After 12 months of treatment, average pain ratings in subjects' primary area of pain decreased from 8.0 cm at baseline to 4.1 cm, and 49% of subjects had 50% reduction in pain (visual analog scale). In addition, functional capacity was increased, and mood and quality of life improved. No confirmed lead migrations were observed, and there was a low rate of infection.

ConclusionsDRG stimulation significantly reduced the severity of subjects' pain and enabled participatory changes that improved quality of life through 12-months postimplant.

Original languageEnglish
Pages (from-to)80-86
Number of pages7
JournalNeuromodulation
Volume22
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • spinal cord stimulation
  • dorsal root ganglion
  • pain
  • quality of life
  • function
  • neuropathic
  • SPINAL-CORD STIMULATION
  • REGIONAL PAIN SYNDROME
  • SYNDROME TYPE-I
  • TRIAL
  • BACK
  • MULTICENTER
  • CHALLENGES
  • MANAGEMENT
  • OUTCOMES
  • SAFETY

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