TY - JOUR
T1 - European interdisciplinary guideline on invasive squamous cell carcinoma of the skin
T2 - Part 1. epidemiology, diagnostics and prevention
AU - Stratigos, Alexander J.
AU - Garbe, Claus
AU - Dessinioti, Clio
AU - Lebbe, Celeste
AU - Bataille, Veronique
AU - Bastholt, Lars
AU - Dreno, Brigitte
AU - Fargnoli, Maria Concetta
AU - Forsea, Ana Maria
AU - Frenard, Cecille
AU - Harwood, Catherine A.
AU - Hauschild, Axel
AU - Hoeller, Christoph
AU - Kandolf-Sekulovic, Lidija
AU - Kaufmann, R.
AU - Kelleners-Smeets, Nicole W. J.
AU - Malvehy, Josep
AU - del Marmol, Veronique
AU - Middleton, Mark R.
AU - Moreno-Ramirez, David
AU - Pellecani, Giovanni
AU - Peris, Ketty
AU - Saiag, Philippe
AU - van den Beuken-van Everdingen, Marieke H. J.
AU - Vieira, Ricardo
AU - Zalaudek, Iris
AU - Eggermont, Alexander M. M.
AU - Grob, Jean-Jacques
AU - European Dermatology Forum (EDF)
AU - European Association of Dermato-Oncology (EADO)
AU - European Organization for Research and Treatment of Cancer (EORTC)
PY - 2020/3
Y1 - 2020/3
N2 - Invasive cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers in the white populations, accounting for 20% of all cutaneous malignancies. Factors implicated in cSCC etiopathogenesis include ultraviolet radiation exposure and chronic photoaging, age, male sex, immunosuppression, smoking and genetic factors. A collaboration of multidisciplinary experts from the European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organisation of Research and Treatment of Cancer (EORTC) was formed to update recommendations on cSCC classification, diagnosis, risk stratification, staging and prevention, based on current literature, staging systems and expert consensus. Common cSCCs are typically indolent tumors, and most have a good prognosis with 5-year cure rates of greater than 90%, and a low rate of metastases (
AB - Invasive cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers in the white populations, accounting for 20% of all cutaneous malignancies. Factors implicated in cSCC etiopathogenesis include ultraviolet radiation exposure and chronic photoaging, age, male sex, immunosuppression, smoking and genetic factors. A collaboration of multidisciplinary experts from the European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organisation of Research and Treatment of Cancer (EORTC) was formed to update recommendations on cSCC classification, diagnosis, risk stratification, staging and prevention, based on current literature, staging systems and expert consensus. Common cSCCs are typically indolent tumors, and most have a good prognosis with 5-year cure rates of greater than 90%, and a low rate of metastases (
KW - Invasive cutaneous squamous cell carcinoma
KW - Low-risk
KW - High-risk common primary cSCC
KW - Locally advanced Cscc
KW - Metastatic cSCC
KW - Diagnosis
KW - Prognosis
KW - Staging
KW - Imaging
KW - Prevention
KW - LYMPH-NODE BIOPSY
KW - ORGAN TRANSPLANT RECIPIENTS
KW - RANDOMIZED CONTROLLED-TRIAL
KW - AMERICAN JOINT COMMITTEE
KW - NONSTEROIDAL ANTIINFLAMMATORY DRUGS
KW - HIGH-RISK
KW - BASAL-CELL
KW - SUN PROTECTION
KW - CANCER PREVENTION
KW - PERINEURAL INVASION
U2 - 10.1016/j.ejca.2020.01.007
DO - 10.1016/j.ejca.2020.01.007
M3 - Article
C2 - 32113941
SN - 0959-8049
VL - 128
SP - 60
EP - 82
JO - European Journal of Cancer
JF - European Journal of Cancer
ER -