ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer

Felipe A. Calvo*, Claudio V. Sole, Harm J. Rutten, Wim J. Dries, Miguel A. Lozano, Mauricio Cambeiro, Philip Poortmans, Luis Gonzalez-Bayon

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Web of Science)

Abstract

Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is a component of irradiation intensification. Long-term cancer control and a higher survival rate were consistently reported in patients who had IORT as a component of their multidisciplinary treatment. The experience reported by expert IORT groups is reviewed and recommendations to guide clinical practice are explained in detail. (c) 2020 Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology.

Original languageEnglish
Pages (from-to)41-48
Number of pages8
JournalClinical and Translational Radiation Oncology
Volume24
DOIs
Publication statusPublished - Sep 2020

Keywords

  • Rectal cancer
  • Recurrent disease
  • Oligo-recurrence
  • Intraoperative radiotherapy
  • Rescue surgery
  • Electron beam
  • SURGICAL RESECTION
  • MULTIMODALITY TREATMENT
  • PELVIC RECURRENCE
  • RADIOTHERAPY IORT
  • ELECTRON-BEAM
  • SURGERY
  • BRACHYTHERAPY
  • CHEMORADIATION
  • REIRRADIATION
  • IRRADIATION

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