Estimates of costs for modelling return on investment from smoking cessation interventions

Marta Trapero-Bertran*, Reiner Leidl, Celia Munoz, Puttarin Kulchaitanaroaj, Kathryn Coyle, Maximilian Prager, Judit Jozwiak-Hagymasy, Kei Long Cheung, Mickael Hiligsmann, Subhash Pokhrel, EQUIPT Study Grp

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Background and aims Modelling return on investment (ROI) from smoking cessation interventions requires estimates of their costs and benefits. This paper describes a standardized method developed to source both economic costs of tobacco smoking and costs of implementing cessation interventions for a Europe-wide ROI model [European study on Quantifying Utility of Investment in Protection from Tobacco model (EQUIPTMOD)]. Design Focused search of administrative and published data. A standardized checklist was developed in order to ensure consistency in methods of data collection. Setting and participants Adult population (15+ years) in Hungary, Netherlands, Germany, Spain and England. For passive smoking-related costs, child population (0-15 years) was also included. Measurements Costs of treating smoking-attributable diseases; productivity losses due to smoking-attributable absenteeism; and costs of implementing smoking cessation interventions. Findings Annual costs (per case) of treating smoking attributable lung cancer were between (sic)5074 (Hungary) and (sic)52106 (Germany); coronary heart disease between (sic)1521 (Spain) and (sic)3955 (Netherlands); chronic obstructive pulmonary disease between (sic)1280 (England) and (sic)4199 (Spain); stroke between (sic)1829 (Hungary) and (sic)14880 (Netherlands). Costs (per recipient) of smoking cessation medications were estimated to be: for standard duration of varenicline between (sic)225 (England) and (sic)465 (Hungary); for bupropion between (sic)25 (Hungary) and (sic)220 (Germany). Costs (per recipient) of providing behavioural support were also wide-ranging: one-toone behavioural support between (sic)34 (Hungary) and (sic)474 (Netherlands); and group-based behavioural support between (sic)12 (Hungary) and (sic)257 (Germany). The costs (per recipient) of delivering brief physician advice were: (sic)24 (England); (sic)9 (Germany); (sic)4 (Hungary); (sic)33 (Netherlands); and (sic)27 (Spain). Conclusions Costs of treating smoking-attributable diseases as well as the costs of implementing smoking cessation interventions vary substantially across Hungary, Netherlands, Germany, Spain and England. Estimates for the costs of these diseases and interventions can contribute to return on investment estimates in support of national or regional policy decisions.
Original languageEnglish
Pages (from-to)32-41
Number of pages10
Publication statusPublished - 1 Jun 2018


  • Cost
  • modelling
  • return on investment
  • smoking cessation
  • tobacco

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