Eradicating Suicide at Its Roots: Preclinical Bases and Clinical Evidence of the Efficacy of Ketamine in the Treatment of Suicidal Behaviors

Domenico De Berardis*, Michele Fornaro, Alessandro Valchera, Marilde Cavuto, Giampaolo Perna, Marco Di Nicola, Gianluca Serafini, Alessandro Carano, Maurizio Pompili, Federica Vellante, Laura Orsolini, Annastasia Fiengo, Antonio Ventriglio, Kim Yong-Ku, Giovanni Martinotti, Massimo Di Giannantonio, Carmine Tomasetti

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Article number2888
Number of pages22
JournalInternational journal of molecular sciences
Volume19
Issue number10
DOIs
Publication statusPublished - 1 Oct 2018

Keywords

  • mood disorders
  • dopamine
  • serotonin
  • glutamate
  • postsynaptic density
  • antipsychotics
  • antidepressants
  • NMDA
  • suicide
  • ketamine
  • esketamine
  • MAJOR DEPRESSION
  • PREFRONTAL CORTEX
  • BIPOLAR DISORDER
  • NMDA RECEPTOR
  • COMPLETED SUICIDE
  • RAPID REDUCTION
  • CELL-GROWTH
  • STRESS
  • MTOR
  • IDEATION

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