Epigenetic modifications in mouse cerebellar Purkinje cells: effects of aging, caloric restriction, and overexpression of superoxide dismutase 1 on 5-methylcytosine and 5-hydroxymethylcytosine

Roy Lardenoije, Daniel L. A. van den Hove, Thomas S. J. Vaessen, Artemis Iatrou, Koen P. V. Meuwissen, Britt T. J. van Hagen, Gunter Kenis, Harry W. M. Steinbusch, Christoph Schmitz, Bart P. F. Rutten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)3079-3089
JournalNeurobiology of Aging
Issue number11
Publication statusPublished - Nov 2015


  • DNA methylation
  • DNA hydroxymethylation
  • Purkinje cells
  • Aging
  • Caloric restriction
  • Antioxidant overexpression

Cite this