Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?

A. Iatrou, G. Kenis, B. P. F. Rutten, K. Lunnon, D. L. A. van den Hove*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)509-523
Number of pages15
JournalCellular and Molecular Life Sciences
Volume74
Issue number3
DOIs
Publication statusPublished - Feb 2017

Keywords

  • Alzheimer's disease
  • Locus coeruleus
  • Raphe nuclei
  • Epigenetics
  • DNA methylation
  • DNA hydroxymethylation
  • MILD COGNITIVE IMPAIRMENT
  • GENOME-WIDE ASSOCIATION
  • DORSAL RAPHE NUCLEUS
  • AMYLOID PRECURSOR PROTEIN
  • BETA-HYDROXYLASE ACTIVITY
  • GLOBAL DNA METHYLATION
  • LOCUS-COERULEUS
  • SENILE-DEMENTIA
  • NEURODEGENERATIVE DISEASES
  • NEUROFIBRILLARY TANGLES

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