(-)-Epicatechin metabolites promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade inflammation

Dragan Milenkovic, Ken Declerck, Yelena Guttman, Zohar Kerem, Sylvain Claude, Antje R Weseler, Aalt Bast, Hagen Schroeter, Christine Morand, Wim Vanden Berghe

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number113699
Number of pages16
JournalBiochemical Pharmacology
Volume173
DOIs
Publication statusPublished - Mar 2020

Keywords

  • Epicatechin metabolite
  • Vascular health
  • Epigenetic
  • Endothelial-immune cell signaling
  • Systemic low-grade inflammation
  • INTRAGENIC DNA METHYLATION
  • C-REACTIVE PROTEIN
  • LYMPHOCYTE RATIO
  • OXIDATIVE STRESS
  • COCOA FLAVANOLS
  • BLOOD-PRESSURE
  • CHOCOLATE
  • RISK
  • HOMOCYSTEINE
  • FLAVONOIDS

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