Eosinophilic enterocolitis diagnosed by means of technetium-99m albumin scintigraphy and treated with budesonide (CIR).

M.G.V.M. Russel, R.N. Zeijen, R.J.M. Brummer, A.P. de Bruine, M.J.P.G. van Kroonenburgh, R.W. Stockbrügger

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Abstract

Eosinophilic enterocolitis diagnosed by means of technetium-99m albumin scintigraphy and treated with budesonide (CIR).

Russel MG, Zeijen RN, Brummer RJ, de Bruine AP, van Kroonenburgh MJ, Stockbrugger RW.

Department of Gastroenterology, University Hospital Maastricht, The Netherlands.

A patient with a 15 year history of diarrhoea of unknown origin is described. Scintigraphy with technetium-99m labelled albumin suggested albumin loss at the terminal ileum and caecum; subsequent colonoscopic biopsies of these macroscopically normal looking areas showed abundant infiltration with eosinophils. A diagnosis of eosinophilic enterocolitis was made. Treatment with prednisolone had good results, but had to be stopped because of severe side effects. Oral cromoglycate and mesalazine were not effective. Budesonide (CIR), a new topically active corticosteroid with very little systemic effects, was at least as effective as prednisolone without producing side effects
Original languageEnglish
Pages (from-to)1490-1492
JournalGut
Volume35
Issue number10
DOIs
Publication statusPublished - 1 Jan 1994

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