Enterovirus and parechovirus infection in children: a brief overview

S. C. M. de Crom; J. W. A. Rossen; A. M. van Furth; C. C. Obihara

doi:10.1007/s00431-016-2725-7

Enterovirus and parechovirus infection in children: a brief overview

S. C. M. de Crom^*
, J. W. A. Rossen
, A. M. van Furth
, C. C. Obihara

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children. Conclusions: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.

Original language	English
Pages (from-to)	1023-1029
Number of pages	7
Journal	European Journal of Pediatrics
Volume	175
Issue number	8
DOIs	https://doi.org/10.1007/s00431-016-2725-7
Publication status	Published - Aug 2016

Keywords

Enterovirus
Parechovirus
Overview
Children
Infection

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10.1007/s00431-016-2725-7Licence: CC BY

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title = "Enterovirus and parechovirus infection in children: a brief overview",

abstract = "Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children. Conclusions: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.",

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AU - de Crom, S. C. M.

AU - Rossen, J. W. A.

AU - van Furth, A. M.

AU - Obihara, C. C.

PY - 2016/8

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N2 - Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children. Conclusions: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.

AB - Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children. Conclusions: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.

KW - Enterovirus

KW - Parechovirus

KW - Overview

KW - Children

KW - Infection

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DO - 10.1007/s00431-016-2725-7

M3 - Article

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JO - European Journal of Pediatrics

JF - European Journal of Pediatrics

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ER -

Enterovirus and parechovirus infection in children: a brief overview

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Keywords

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