Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure)

Susan Stienen, Joao Pedro Ferreira, Masatake Kobayashi, Gregoire Preud'homme, Daniela Dobre, Jean-Loup Machu, Kevin Duarte, Emmanuel Bresso, Marie-Dominique Devignes, Natalia Lopez, Nicolas Girerd, Svend Aakhus, Giuseppe Ambrosio, Hans-Peter Brunner-La Rocca, Ricardo Fontes-Carvalho, Alan G. Fraser, Loek Van Heerebeek, Stephane Heymans, Gilles De Keulenaer, Paolo MarinoKenneth McDonald, Alexandre Mebazaa, Zoltan Papp, Riccardo Raddino, Carsten Tschoepe, Walter J. Paulus, Faiez Zannad, Patrick Rossignol*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)201-211
Number of pages11
JournalBiomarkers
Volume25
Issue number2
DOIs
Publication statusPublished - 17 Feb 2020

Keywords

  • HFPEF
  • machine learning
  • biomarkers
  • cluster analysis
  • phenotype
  • complex-network analysis
  • HEPARIN-BINDING PROTEIN
  • ANGIOPOIETIN RECEPTOR TIE-2
  • BRAIN NATRIURETIC PEPTIDE
  • GROWTH-FACTOR
  • PLASMA ANGIOPOIETIN-1
  • L-SELECTIN
  • GRANULYSIN
  • EXPRESSION
  • DISEASE
  • DATABASE

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