Abstract
A material-based bottom-up approach is proposed towards an assembly of cells and engineered micro-objects at the macroscale. We show how shape, size and wettability of engineered micro-objects play an important role in the behavior of cells on these objects. This approach can, among other applications, be used as a tool to engineer complex 3D tissues of clinically relevant size.
Original language | English |
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Pages (from-to) | 2592-2599 |
Journal | Advanced Materials |
Volume | 26 |
Issue number | 16 |
DOIs | |
Publication status | Published - Apr 2014 |
Keywords
- bottom-up tissue engineering
- micro-objects
- human mesenchymal stromal cells
- cell aggregates
- biofabrication